Embryology Flashcards
The Intermediate Plate Mesoderm forms the
Urogenital System
Gastrulation happens in
Week 3
Neuralation happens in
Week 3
Somite Formation happens in
Week 3
Maturation of organ systems happens in
Week 9 onwards
Pronephros develops what set of kidneys
Cervical Region
Mesonephros develops what set of kidneys
Thoracoculmbar
Metanephros develops what set of kidneys
Pelvic Region
What happens in Week 5 Embryology Repro
Genital Gonadal Ridge Formation
Germ cells migrate into
Indifferent Gonad in Week 6
What tube comes para-mesonephric duct
Epithelium of Mesonephros tube
What develops lateral to developing gonads and mesonephric duct
Para-Mesonephric Duct
Wolffian Duct is also known as
Mesonephric duct
Mullerian Duct is also known as
Paramesonephric Duct
Gonad forms
Testis
Mesonephric Duct develops into (3)
Epididymis, Vas Deferens and Seminal Vesicle
Urogenital Sinus forms what in males
Bladder, Urethra and Prostate
Gonad in the female forms
Ovary
Paramesonpehric Duct in females forms
Fallopian Tube, Uterus, Cervix Part of Vagina
Urogenital Sinus forms what in females
Bladder and Lower Vagina
Primordial Supporting Cells expresses
SRY Encodes
Primordial Supporting cells transforms SRY into
Sertoli Cells
Sertoli Cells secrete
Mullerian Inhibiting Substance
What does Paramesonephric Duct do in males
Degenerates
Leydig cells produces
Testosterone
Mullerian Inhibiting Substance transforms Mesenchymal cells between cords to form
Leydig Cells
Leydig Cells and Sertoli Cells can be found in what histology
Testis
What happens in week 5 of testis development
Primary Sex Cords, Medulla and Cortex
What happens in week 7 of testis development
TDF Stimulates Primary Sex Cords and extends into medulla seminferous cords tubules
What between cords gives rise to Interstitial cells of leydig
Mesenchyme
By week 8 what does Leydig Cells Produce
Testosterone
In males what does paramesonephric duct do
Degenerates
Seminal Vesicle is an outgrowth from
Caudal end of mesonephric duct
Prostate is an outgrowth from
Urethra
In the presence of what does gonad develop into testis
TDF
What two things does female fetus not have that male does
No SRY Region and No TDF region
By 10 weeks secondary sex cords develop from
Surface Epithelium
Primordial Follicles forms from
16 Weeks
By what month have all follicles formed in female development of ovary
7 Month
Oocytes enter meiosis and are arrested in what meiotic division in development of ovary
Prophase 1st Meiotic Division
After puberty hormonal influences stimulate how many follicles
12-15 follicles per 28 day cycle
Absence of testosterone in females causes
Degeneration of mesonephros and mesonpehric duct
What gives rise to female genital tract
Paramesonephric Duct
Which end of paramesonephric duct becomes associated with ovary
Cranial (open funnel)
Which part of paramesonephric duct (uterovaginal primordial) becomes uterus and superior vagina
Caudal End
Inferior Part of Vagina forms from
Urogenital sinus
Gonads initially forms where
Lumbar Region
At Week 7 where is Testis
T10
At week 12 where is testis
level of deep inguinal ring until 7th month
When do testis enter scrotum
39 Weeks
Where is ovary located in week 7
T10
Week is ovary located in week 12
Broad Ligament
Round ligament is drawn through inguinal canal to attach to
Labrum Majorum
How to Manage Undescended Testis
Orchiopexy
Paramesonephric Dut becomes
Fallopian Tube, Uterus, Cervix and Vagina
Sperm can survive
5 Days
Oocyte can survive
24 Hours
Acrosome reacts with what in fertilisation
Zona Pellucida and Periviteline Space
What happens in early embryo development day 1
formation of pronuclei
What happens in early embryo development day 2
first cell division
What happens in early embryo development day 3
cell division continues
What happens in early embryo development day 4
formation of morula
What happens in early embryo development day 5
blastocyst forms
Early embryo enters uterine cavity in what phase
morula
Trophoectoderm cells produce
Protease to dissolve zona
Trophoblast of Blastocyst adheres to
Epithelial Layer of Maternal Endometrium
Uterine Spiral arteries remodel the
Trophoblast
Hatching of embryo from Zona Pellucida is when
5th Day after Fertilisation
What is a pre-requisite for trophoblast invasion and placentation
Transformation of Stromal Cells under effect of Progesterone
Stromal Cells are converted into
Decidual
What are uterine natural killer cells also known as
Decidual Leukocytes
Trophoblast invades from
Primary Chorionic Villi
Embryo development where blastocyst reaches is what day
Day 5
Embryogenesis happens when
First 8 Weeks of Embryo development post fertilisation
Fertilised egg forms blastocyst when
Day 5
Bilaminar Germ and Amniotic Sac form when
Week 2-3
Yolk Sac is formed when
Week 2-3
Extraembryonic Mesoderm and Chorionic Cavity forms when
Week 2-3
Differentiation of Bilaminar Disc into Trilaminar Structure is when
Week 3-4
Organogenesis happens when
Week 5-8
Fetal Period Begins
Week 8
Bilaminar Disc consists of
Epiblast and Hypoblast
Epiblast undergoes what to form three germ layers
Gastrulation
Hypoblast forms
Extraembryonic Mesoderm
Inner Layer Cytotrophoblast forms
Chorionic Villi
What kind of epithelium in bilaminar epiblast
Columnar
What kind of epithelium in hypoblast
Hypoblast
The Yolk Sac forms on
Hypoblast
Amniotic Cavity forms on the
Epiblast
Epiblast differentiates into
Ectoderm, Mesoderm and Endoderm
Where does Primitive Streak appear from
Caudal Epiblast
Which forms Endoderm
Epiblast Cells migrate into Hypoblast
What forms Mesoderm
Epiblast Cells through Primitive Streak between Epiblast and Hypoblast/endoderm
The Trilaminar Disc is also called
Gastrula
The Ectoderm forms the (8)
Epidermis CNS Peripheral Nervous Hair Nails Adrenal Medulla Pituitary Gland Teeth Enamel
The Mesoderm forms the (9)
Dermis MSK CVS Kidneys Ureters Bladder Gonads Adrenal Cortex Pleura
The Endoforms the (7)
GI Tract Parenchyma liver Pancreas Thyroid Tonsils Bladder Urethra
Intermediate Mesoderm forms
Kidney, Ureter, Gonads
What happens in Dizygotic Pregnancy
Two or more eggs fertilising and implanting, non identical
What happens in Monozygotic Pregnancy
One Embryo Splitting
Identical Twins
In Day 1-4 Division Day Post Fertilisation Type of Pregnancy and Incidence
Dichorionic Diamniotic 20% (Seperate Placenta and Amniotic Sac)
In Day 5-8 Division Day Post Fertilisation Type of Pregnancy and Incidence
Monochorionic diamniotic (share placenta, separate amniotic sac) 75%
In Day 7-14 Division Day Post Fertilisation Type of Pregnancy and Incidence
Monochorionic monoamniotic (share placenta and amniotic sac) 5%
In Day >14 Division Day Post Fertilisation Type of pregnancy and Incidence
Conjoined Twins <1%
In Monozygotic Pregnancy what happens to Placenta
Shared
Embryogenesis when
First 8 Weeks Post Fertilisation
The caudal end of enfolded yolk sac is known as
Cloaca
The Cloaca is divided by urorectal septum to form
Urogenital Sinus
AnaL Canal
Urogenital Sinus forms
Bladder and Urethra
The indifferent gonad develops in
Gonadal Ridge
What forms Primitive Sex Cords
Epithelium of Gonadal Ridge
Which chromosome contains SRY gene
Y
What forms Testis Cords
Primitive Sex Cords entering into medulla
Leydig cells are produced from
Intermediate Mesoderm
Leydig cells produce testotestone from
Week 8
Mesonephric Duct also called Wolffian Ducts drain
Mesonephros into Cloca
What forms bladder
Mesonephric Duct also called Wolffian Ducts
What forms the Labia Minora
Urogenital Folds
What forms Labia Majora
Labioscrotal Folds
What forms Clitoris
Genital Tubercle
In females paramesonephric duct forms
Uterus and Upper 2/3rd of Vagina
Lower 1/3rd of vagina forms form
Urogenital Sinus
Mesonephric/Wolffian Duct develops under testosterone effect to form
Epididymis, Vas Deferens and Seminal Vesicles