electron transport chain Flashcards

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1
Q

what happens in the final stage of respiration

A

reduced NAD or FAD from glycolysis and the krebs cycle is used with oxygen to make ATP in process called oxidative phosphorylation

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2
Q

what does oxidative phosphorylation involve

A

an electron transport chain

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3
Q

what is an electron transport chain

A

series of electron carrier molecules down which electron from reduced NAD or FAD are passed

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4
Q

what also happens the same time as the electron chain transport

A

the hydrogen ions protons left behind are used in chemiosmosis to supply the energy to synthesise ATP

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5
Q

thinking of the electron transport chain as being at different energy levels

A

-the first member of the chain is the highest level with steps down
-each electron is passed down from one energy level to another driving production of ATP

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6
Q

what is ATP production know as

A

oxidative phosphorylation because ADP is phosphorylated in process that depends on presence of oxygen

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7
Q

first hydrogen acceptor in electron transport chain

A

coenzymes NAD and FAD
-act as hydrogen acceptors for hydrogen released in krebs cycle
-one molecule of ATP produced when FAD is reduced and accepts hydrogen from NADH which becomes oxidised

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8
Q

second hydrogen acceptor

A

oxygen
-when oxygen is reduced water if formed and the chain is at its end

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9
Q

what are cytochromes

A

protein pigments with iron group like heamoglobin

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10
Q

what are cytochromes involved in

A

in electron transport and are reduced by electrons from reduced FAD and reduced NAD which is oxidised again
- molecule of ATP is produced at this stage

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11
Q

what is cytochrome oxidase

A

-enzyme that receives electrons from cytochromes and is reduced as cytochromes are oxidised
-molecule of ATP also produced at this stage

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12
Q

hydrogen entering from reduced NAD

A

each molecule of hydrogen passing along electron transport chain from reduced NAD enough energy released to make 3 molecules of ATP

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13
Q

hydrogen entering from reduced FAD

A

-when hydrogen enters chain from reduced FAD only 2 molecules of ATP reduced

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14
Q

where do link reaction and krebs cycle take place

A

matrix of the mitochondria

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15
Q

where do the electron transport chain and ATP production take place

A

the inner membrane of the mitochondria

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16
Q

site of ATPase enzymes

A

-closely packed stalked particles

17
Q

what did Peter Mitchell describe

A

the link between electrons that are passed down the electron transport chain and the production of ATP

18
Q

what does the chemiosmotic theory explain

A

explains what happens to the hydrogen ions that are left behind when electrons are passed along the electron transport chain and how the movement of hydrogen ions is coupled to the actual production of ATP

19
Q

what does Mitchell propose

A

that hydrogen ions are actively transported into the space between the inner and outer mitochondrial membranes using the energy provides as the electrons pass along the transport chain

20
Q

what does active transport of hydrogen ions across inner membrane result in

A

a different hydrogen ion concentration on each side of the membrane

21
Q

consequences of having a concentration gradient of hydrogen ions across membranes

A

the membrane space has a higher concentration of hydrogen ions that the matrix so there is a concentration gradient across the membrane
-also pH gradient
-because positive ions concentrated in membrane space there is electrochemical gradient

22
Q

consequences of various hydrogen concentration across membranes

A

mean there is tendency for hydrogen ions to move back into the matrix

23
Q

whats the only way hydrogen ions can move back into the matrix

A

-through special pores found on stalked particles and have ATPase enzymes associated with them

24
Q

what happens as hydrogen ions move across different concentration gradients

A

-as they move along electrical, concentration and pH gradients their energy is used to drive synthesis of ATP

25
Q

1960 accepted model of formation of ATP

A

was that a high energy phosphate group was directly transferred to ADP from another intermediate- like end of glycolysis when pyruvate formed
-but intermediate not found and chemiosmotic theory accepted

26
Q

evolution of cellular respiration

A

-evolved to produce energy in form of ATP for use in cells
-fact that same process in almost all living organisms means it evolved at early stages of development of organisms and very effective

27
Q

how much ATP is gained during its oxidation of one molecule of glucose

A

-38 molecules but 2 molecules used to transport reduced NAD molecules produced by glycolysis through mitochondrial membrane leaving 36 for body cells

28
Q

how much ATP molecules does oxidation of 2 molecules of reduced NAD provide energy for

A

process makes about 5 molecules of ATP

29
Q

how much ATP does oxidation of 2 molecules of reduced FAD make

A

3 molecules of ATP

30
Q

overall yield of ATP in aerobic respiration

A

31 molecules