electrolytes 2 Flashcards
pH up to last slide
why regulation of H+ is needed?
all activities of almost all enzyme systems are influenced by H+ concentration
H+ concentrations are kept at low levels ___
0.00004 mEq/L
hydrogen concentration is expressed in?
pH units
pH is ___ to the H+ concentration
inversely related
normal pH of arterial blood
7.4
normal pH of venous blood
7.35
single free proton released form a hydrogen atom
hydrogen ion
systems that regulate H+ concentration
- buffer systems
- respiratory regulation
- the kidneys (renal regulation)
limits pH changes when strong acids/bases are introduced
any substance that can reversibly bind h+
buffer
examples of buffer
- bicarbonate
- proteins
- phosphate buffers
main extracellular buffer that is affected by lungs and kidneys
Bicarbonate-Carbonic Acid buffer system
Bicarbonate-Carbonic Acid buffer system is accelerated by?
carbonic anhydrase
Bicarbonate-Carbonic Acid buffer system (formula (?))
CO2 + H2O <—> H2CO3 <—> H+ + HCO3
second line of defense against acid-base disturbances is control of?
extracellular fluid CO2
what mechanism?
alveolar ventilation provides the oxygen needed for oxidative metabolism and eliminates the CO2 produced by metabolic process
respiratory regulation