Electrical Activity Of The Heart Flashcards
What is the physical connection between cardiac muscle cells
Desmosomes
What is the electrical connectionz between cardiac muscle cells
Gap junctions
Why can’t cardiac muscle exhibit tetanus (sustained contractions)
Cardiac muscle has a long refractory period
What is a synctium
A fusion of cells, in the heart by intercalated discs
Action potential time of cardiac Vs skeletal muscle
250ms
2ms in skeletal
How can Ca entry from outside the cell regulate contraction
Troponin is not fully saturated so contraction strength can be varied
Cells with unstable resting potentials
Act as pacemaker cells, rely on the increase of L-type Ca ions instead of Na ions as they have little Na channels
Effect of Ca channel blockers on heart
Decrease force of contraction
Effect of cardiac glycosides on the heart
Increase force of contraction
Effect of body temperature on the heart
Increases 10 beats per minute per degrees
Effect of hyperkalemia and hypokalemia on the heart
Fibrillation and heart block
Effect of hypercalcaemia on the heart
Increased heart rate and force of contraction
Effect of hypocalcemia on the heart
Decreased heart rate and force of contraction
Effect of hypocalcemia on the heart
Decreased heart rate and force of contraction
The sinoatrial node
First pacemaker and start of contraction. Conducts at 0.5m/s and is in the right atrium