Eimeria spp. (1) Flashcards

1
Q

How do you identify in sheep and goats?

A

Sheep

 - E. crandallis
 - E. ovinoidalis

Goats

 - E. ninakohlyakimovae 
 - E. caprina
 - E. arloingi 
 - E. christenseni
 - E. hirci
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2
Q

Explain the life cycle in sheep and goats

A

Sporulated oocyst ingested

Excystation of oocyst

Merogony

Gametogony

Fertilization

Excretion

Unsporulated oocyst

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3
Q

What is the site of infection?

A

Small and large intestines

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4
Q

Describe the Pathogenesis

A

Inflammatory changes

Disruption of mucosa

Outbreaks associated with:

 - Lambs 1-3 months old
 - Lot-fed animals
 - Irrigated pastures
 - Corralling 
 - Stress
        - Transportation 
        - Temperature changes
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5
Q

What are the clinical signs in sheep and goats?

A

Diarrhea - putty-like to watery to bloody (E. ovinoidalis)

Leads to dehydration and weakness

Severity related to species, parasite density and number of cells affected

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6
Q

How do you diagnose in sheep and goats?

A

History

Clinical signs

Fecal flotation to detect Oocysts

Sporulation for species

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7
Q

How do you treat and prevent in sheep and goats?

A

Coccidiasis is inevitable

Coccidiosis is preventable

Risk factors

 - Overcrowding (Feedlot situations)
 - Unhygienic conditions (Feed contaminated by feces)
 - Mixing of different age groups
 - Stress
        - Inclement weather
        - Transport

Prevented by improving management of animals

 - Preventing overcrowding
 - Improving hygiene

Control of Coccidiosis
- Animals sufficiently exposed to develop immunity without
developing overt clinical disease
- Coccidiostats used prophylactically to achieve this purpose

Treatment of isolated cases
- Require both anticoccidial medication and supportive therapy to
rehydrate
- Prevent secondary bacterial infection

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8
Q

In birds which is more common?

A

Coccidiasis is more common than coccidiosis

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9
Q

How do you identify in birds?

A

Description of Oocysts are insufficient for species diagnosis

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10
Q

Explain the life cycle in birds

A

Sporulated oocyst ingested

Excystation of oocyst

Merogony

Gametogony

Fertilization

Excretion

Unsporulated oocyst

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11
Q

What are the sites of infection in birds?

A

Small and large intestines

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12
Q

Describe the Pathogenesis in birds

A

Bloody droppings

Dehydration

E. tenella most pathogenic species in young chicks

High death rate

Recovered birds may be chronically ill due to persistent core of clotted blood in cecum

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13
Q

How do you diagnose in birds?

A

Oocysts can be seen in feces

 - Speciation difficult even with sporulation
 - Relatively site specific (different areas of small/large intestines)

Best accomplished by necropsy examination of representative number of birds
- Location of major lesions gives indication of species

E. tenella in ceca

E. necatrix in small intestine

E. brunette in ileum, cecum, and rectum

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14
Q

How do you treat and prevent in birds?

A

Poultry industry loses more than $700 million annually

Challenges:

 - Confined-host rearing conditions 
        - High levels of infection
        - Development of drug-resistant Coccidia strains

Few management practice include:
- Anticoccidial drugs mixed in feed - limit high levels of infection
- Keep chicks, feed, water away from droppings
- Roost birds over wire netting
- Place water vessels on wire frames to eliminate concentration of
wet droppings
- Keep litter dry and stir frequently
- Remove wet spots, replace with dry litter
- Avoid overcrowding
- If coccidiosis does break out, start treatment immediately

Several coccidiostats available
- Withdrawal periods and contraindications should be strictly
followed

Emergence of drug resistant strains

 - Methods used to avoid development of drug resistant strains:
        - Switching classes of drugs
        - "Shuttle program" 
               - Planned switch of drug in middle of bird's growth period

Control

 - Use of vaccines
        - Used mostly for egg laying birds
        - Chicks treated soon after hatching 
               - Lifelong immunity
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15
Q

Describe in chickens

A

Only some species cause severe clinical disease

Oocysts range: 12x30 to 13x40 micro m

E. tenella, E. brunetti, E. necatrix - most pathogenic

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16
Q

What is the site of infection for E. tenella?

A

Develops in cells of ceca

17
Q

Describe the Pathogenesis of E. tenella

A

Acute infection most commonly in young chicks

Characterized by presence of blood in droppings

High morbidity and mortality

First noticeable about 3 days after infection
- Chickens droop, stop feeding, huddle together

Day 4

 - Blood in droppings
        - Increases until day 9

Death occurs unexpectedly
- Due to excessive blood loss

Birds who recover may develop chronic illness as a result of persistent cecal core (of clotted blood)
- Core usually detaches in 8-10 days, shed in droppings

Sloughing of epithelium

Plugged cecum due to clotted blood and cell debris, causing necrosis

18
Q

Explain the life cycle of E. tenella

A

Infection

Merogony I, II, III(IV)

Gametogony

Sporogony

19
Q

How do you treat E. tenella?

A

Prophylaxis using coccidiostats in food and water

Vaccines, effective with species specificity

Annual expenditures for coccidiostats worldwide are estimated to be $250-300 million

20
Q

Describe the site of infection of E. necatrix

A

Small intestines (early stages)

Cecum (sexual stages)

21
Q

Describe the Pathogenesis of E. necatrix

A

Bloody droppings

Dehydration

Cecal coccidiosis

22
Q

What is the site of infection of E. acervulina/E. maxima?

A

Upper part of small intestine

23
Q

Describe the Pathogenesis of E. acervulina/E. maxima

A

Subclinical coccidiosis

Marked weight loss

24
Q

Describe Eimeria in turkeys

A

Infections most as pathogenic

E. adenoides, E. meleagrimitis, E. galloparvonis, E. dispersa

Oocyst range: 16x19 micro m to 21x26 micro m

All ages are susceptible to primary infections

Birds older than 6-8 weeks more resistant

25
Q

What are the hosts?

A

Sheep

Goats

Birds

Cattle

26
Q

How do you identify in cattle?

A

Unsporulated oocyst in feces

Sporulate for identification

27
Q

Explain the life cycle in cattle

A

Sporulated oocyst ingested

Excystation of oocyst

Merogony

Gametogony

Fertilization

Excretion

Unsporulated oocyst

E. bovis
- PPP: 15-20 days
- 1st generation schizont: endothelial cells of lacteals of small
intestine
- 2nd generation schizont: epithelial cells of large intestine
- Gametogony: epithelial cells of large intestine

E. zuernii
- PPP: 15-20 days
- 1st generation schizont: Lamina propria cells
- 2nd generation schizont: Epithelial cells of small (very few) and
large intestine
- Gametogony: epithelial cells of small and large intestines

28
Q

What are the sites of infection in cattle?

A

Small and large intestines

Lesions in large intestines

29
Q

Describe the Pathogenesis in cattle

A

Inflammatory changes in mucosa

Disruption of mucosa of large intestines

30
Q

Describe the clinical signs in cattle

A

Diarrhea (mild to severe)

 - Profuse
 - Watery
 - Bloody
 - Projectile

Severity related to parasite density and number of cells affected

31
Q

How do you diagnose in cattle?

A

Fecal flotation to detect Oocysts

32
Q

How do you treat and prevent in cattle?

A

Coccidiasis is inevitable - immunity

Coccidiosis is preventable

 - Coccidiostats
 - Hygiene