Effectiveness of TB Drugs Flashcards
Drugs not effective against intracellular bugs
Streptomycin
Drugs effective against intracellular bugs
Isoniazid
Rifampin
Pyrazinamide
Ethambutol
Drugs that are bactericidal
Rifampin
Streptomycin
Drugs that are bacteriostatic
Isoniazid
Pyrazinamide
Ethambutol
Drugs excreted in urine?
Streptomycin
Pyrazinamide
Ethambutol
Which drug should not be used concurrently with HIV treatments (protease inhibitors and delavirdine)?
Rifampin
The only drug given as prophylaxis and latent treatment?
Isoniazid
Contraindicated in pregnancy and newborns. Can cause deafness.
Streptomycin
This has good bioavailability, is metabolized in the liver, and is excreted in the urine.
Pyrazinamide
This can cross the blood brain barrier when meninges are inflamed.
Ethambutol
Usual treatment regimen for TB?
RIPE Rifampin Isoniazid Pyrazinamide Ethambutol