Anti-inflammatory Class Mechanisms

Question 0

Second generation antihistamines

Answer 0

H1 antagonist

Question 1

First generation antihistamines

Answer 1

Blocks H1 receptors

Some muscarinic, alpha adrenergic and serotonin blocking effects

Question 2

Methylxanthines

Answer 2

Raises intracellular cAMP

Blocks adenosine receptors

Question 3

Cromolyn

Answer 3

Blocks mast cell degranulation of histamine

Question 4

Selective B2 agonists

Answer 4

Binds B2 and increases cAMP

Question 5

Nasal Steroids

Answer 5

Decrease inflammatory cells through decreasing gene transcription
Decrease immune response to allergens

Question 6

Omalizumab

Answer 6

Blocks IgE binding with mast cells and basophils

Also decreases IgE receptors

Question 7

Muscarinic antagonists

Answer 7

Blocks parasympathetic pathway bronchoconstriction

Question 8

Zileuton

Answer 8

Inhibits Lipoxygenase, preventing leukotriene formation

Question 9

Zafirlukast

Montelukast

Answer 9

Blocks leukotriene receptors