effect of recreational drugs

Question 1

what neurotransmitter is released when exposed to a rewarding stimulus

Answer 1

dopamine

Question 2

what pathway is often most associated with reward

Answer 2

mesolimotic dopamine pathway

Question 3

when reward is activated where does dopamine levels rise

Answer 3

nucleus accumbens

Question 4

how does cocaine effect the dopamine levels

Answer 4

cocaine blocks the binding site of the re-uptake receptors and this stops the re-uptake of dopamine back into the pre-synaptic neuron, causing excess dopmaine

Question 5

how long does a high last for in cocaine

Answer 5

15-30 minutes

Question 6

why can addicts of cocaine never have the same euphoric feeling as the first time again

Answer 6

the receptors had been damaged, so will had to take more to substitute for the lack of receptors available

Question 7

give 3 symptoms of the withdrawl of cocaine

Answer 7

anxiety
irritability
paranoia

Question 8

describe how amphetamines work

Answer 8

amphetamine imitates dopamine

forces dopamine into synapse either by diffusion or suing transport in reverse

dopamine in the synapse is amplified leads to excess binding, creating a high

Question 9

what affect does amphetamine have on dopamine

Answer 9

excess dopamine

Question 10

what is glutamate and how is it effected when taking amphetamines

Answer 10

glutamate regulates dopamine

amphetamine reduces the effect of dopamine, which increases levels of dopamine