eczematous d/o Flashcards
what does dermatitis mean
inflamed skin
cause of atopic dermatitis/eczema
imbalance of immune system w/ TH2 predominance
which dermatitis is associated w/ other forms of atopy like asthma and allergic rhinitis
atopic dermatitis (eczema)
what bacteria aggrevates eczema
s. aureus
filaggrin defect/barrier dysfunction and repeated allergen exposure
eczema pathogenesis
describe eczema
scaly, ill-defined red patches; may be lichenified
infant vs adult location for eczema
infant: extensor arms, legs, butt
adult: neck, flexor areas
both: face
on darker skin its more likely to be present with associated pityriasis alba (post-inflammatory hypopig.)
eczema
how is eczema treated
barrier repair & maintenance
dilute bleach baths if crusted
antihistamines for other atopy
topical steroids for breakthrough
consequence of having eczema and being exposed to herpes?
eczema herpetiform (severe widespread lesions)
delayed TH1/ type IV hypersensitivity where theres an itchy rash affecting area exposed to allergen
allergic contact dermatitis
what type of molecules are most allergens?
haptens– they bind to native proteins
list 4 common allergens
nickel
fragrances
preservatives
topical abx (neomycin)
timeline of rash for contact dermatitis
takes 1-2 wks for sensitization & 24-48 hrs to 4-7 days on re-exposure
2-7 days after re-exposure they have itch red papules & vesicles. what is this the clinical features of?
contact dermatitis
describe nummular dermatitis and where it is & what it is likely related to
sharply defined, discoid or circular coin shaped & itchy
on lower legs and trunk
likely related to dry skin