AAD blisters Flashcards

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1
Q

Diffusely scattered vesicles on erythematous base; can be extensive or severe

A

chicken pox

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2
Q

2 ways to confirm chickenpox dx

A

tzanck prep
DFA or PCR

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3
Q

grouped vesicles on erythematous base esp on trunk; preceded by pain or burning

A

herpes zoster (shingles)

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4
Q

Painful, grouped vesicles on erythematous base; tends to be in same place

A

HSV

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5
Q

signs of HSV on erosions in clinic (2)

A

BRIGHT RED RIM on erosion
pain & recurrence

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6
Q

test to differentiate HSV from shingles that works on both vesicles and erosions

A

DFA (direct fluorescent antibody) test

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7
Q

test to reveal PREVIOUS exposure to HSV

A

herpes specific IgG antibody (Herpselect)

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8
Q

3 manifestations of neonatal HSV

A

localized skin, eye and mouth (SEM
CNS +/- SEM
Disseminated

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9
Q

why is early dx and tx of neonatal HSV important?

A

tx can prevent it from going from localized SEM to CNS & disseminated

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10
Q

Multiple, red painful blisters with red borders on fingers; may be pustular

A

herpetic whitlow

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11
Q

bacterial infection caused by gram +; usually S. aureus toxin; mostly in kids

A

bullous impetigo

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12
Q

a generalized form of exotoxin-mediated dz; Toxin in blood causes widespread superficial blisters where skin peels away in sheets

A

staph scalded skin syndrome

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13
Q

results of wound cultures from erosions with staph scalded skin syndrome

A

negative

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14
Q

two populations at risk for staph scalded skin syndrome

A

kids under 2 yrs
adult w/ renal dz

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15
Q

when do you refer to derm with staph scalded skin syndrome

A

extensive blistering!

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16
Q

autoantibodies to desmogleins resulting in SUPERFICIAL bullae and erosions; rarely see intact bullae and usually in adults

A

pemphigus vulgaris

17
Q

how is pemphigus vulgaris & bullous pemphigoid diagnosed

A

direct immunofluorescene & derm consult

18
Q

autoantibodies to parts of hemidesmosome resulting in DEEP,TENSE bullae

A

bullous pemphigoid

19
Q

test to differentiate HSV 1 and 2 and VZV & how long does results take

A

DFA– 2 days

20
Q

localized vesicles on mouth/nose/eyes could be either ___ or _____ (2 ddx)

A

HSV or impetigo

21
Q

localized vesicles on chest, back in dermatomal pattern could be (1ddx)

A

VZV

22
Q

localized vesicles on fingers could be ___ (3 ddx)

A

herpetic whitlow
dyshidrotic eczema
contact dermatitis

23
Q

localized vesicles on arms and legs could be (2 ddx)

A

VZV if dermatomal
contact dermatitis

24
Q

localized vesicles on genitalia or bathing suit (1 ddx)

A

HSV

25
Q

localized vesicles on feet could be (3 ddx)

A

dyshyrosis
tinea pedis
allergic contact dermatitis

26
Q

3 conditions where it itches before onset of localized vesicles

A

allergic contact
dyshidrosis
VZV

27
Q

3 conditions where there is trauma before onset of localized vesicles

A

friction blister
pressure ulcer
cryotherapy

28
Q

oral agent for genital HSV and recurrent herpes liablis; can be used for suppressive therapy; Herpetic whitlow

A

Acyclovir

29
Q

oral agent used for recurrent episodes of genital HSV; converted to acyclovir

A

Valacyclovir

30
Q

oral agent used for recurrent HSV; biotransformed into active penciclovir topical agent

A

Famciclovir