AAD blisters

Question 1

Diffusely scattered vesicles on erythematous base; can be extensive or severe

Answer 1

chicken pox

Question 2

2 ways to confirm chickenpox dx

Answer 2

tzanck prep
DFA or PCR

Question 3

grouped vesicles on erythematous base esp on trunk; preceded by pain or burning

Answer 3

herpes zoster (shingles)

Question 4

Painful, grouped vesicles on erythematous base; tends to be in same place

Answer 4

HSV

Question 5

signs of HSV on erosions in clinic (2)

Answer 5

BRIGHT RED RIM on erosion
pain & recurrence

Question 6

test to differentiate HSV from shingles that works on both vesicles and erosions

Answer 6

DFA (direct fluorescent antibody) test

Question 7

test to reveal PREVIOUS exposure to HSV

Answer 7

herpes specific IgG antibody (Herpselect)

Question 8

3 manifestations of neonatal HSV

Answer 8

localized skin, eye and mouth (SEM
CNS +/- SEM
Disseminated

Question 9

why is early dx and tx of neonatal HSV important?

Answer 9

tx can prevent it from going from localized SEM to CNS & disseminated

Question 10

Multiple, red painful blisters with red borders on fingers; may be pustular

Answer 10

herpetic whitlow

Question 11

bacterial infection caused by gram +; usually S. aureus toxin; mostly in kids

Answer 11

bullous impetigo

Question 12

a generalized form of exotoxin-mediated dz; Toxin in blood causes widespread superficial blisters where skin peels away in sheets

Answer 12

staph scalded skin syndrome

Question 13

results of wound cultures from erosions with staph scalded skin syndrome

Answer 13

negative

Question 14

two populations at risk for staph scalded skin syndrome

Answer 14

kids under 2 yrs
adult w/ renal dz

Question 15

when do you refer to derm with staph scalded skin syndrome

Answer 15

extensive blistering!

Question 16

autoantibodies to desmogleins resulting in SUPERFICIAL bullae and erosions; rarely see intact bullae and usually in adults

Answer 16

pemphigus vulgaris

Question 17

how is pemphigus vulgaris & bullous pemphigoid diagnosed

Answer 17

direct immunofluorescene & derm consult

Question 18

autoantibodies to parts of hemidesmosome resulting in DEEP,TENSE bullae

Answer 18

bullous pemphigoid

Question 19

test to differentiate HSV 1 and 2 and VZV & how long does results take

Answer 19

DFA– 2 days

Question 20

localized vesicles on mouth/nose/eyes could be either ___ or _____ (2 ddx)

Answer 20

HSV or impetigo

Question 21

localized vesicles on chest, back in dermatomal pattern could be (1ddx)

Answer 21

VZV

Question 22

localized vesicles on fingers could be ___ (3 ddx)

Answer 22

herpetic whitlow
dyshidrotic eczema
contact dermatitis

Question 23

localized vesicles on arms and legs could be (2 ddx)

Answer 23

VZV if dermatomal
contact dermatitis

Question 24

localized vesicles on genitalia or bathing suit (1 ddx)

Answer 24

HSV

Question 25

localized vesicles on feet could be (3 ddx)

Answer 25

dyshyrosis
tinea pedis
allergic contact dermatitis

Question 26

3 conditions where it itches before onset of localized vesicles

Answer 26

allergic contact
dyshidrosis
VZV

Question 27

3 conditions where there is trauma before onset of localized vesicles

Answer 27

friction blister
pressure ulcer
cryotherapy

Question 28

oral agent for genital HSV and recurrent herpes liablis; can be used for suppressive therapy; Herpetic whitlow

Answer 28

Acyclovir

Question 29

oral agent used for recurrent episodes of genital HSV; converted to acyclovir

Answer 29

Valacyclovir

Question 30

oral agent used for recurrent HSV; biotransformed into active penciclovir topical agent

Answer 30

Famciclovir