Ectopic Pregnancy Flashcards
95% of ectopic pregnancy is situated in
fallopian
The most common area of ectopic implantation is the
Ampulla bec it is the most dilated part
Isthmus
Risk factors for Ectopic Pregnancy
History of surgery to the fallopian tube
Sexually transmitted disease
Salpingitis isthmica nodosa
DES
Infertility and ART (atypical; cornual, abdominal, cervical)
Smoking - independent risk factor
Contraceptive Method Failures - tubal sterilization, IUD, and progestin-only contraceptives
Epithelium-lined diverticula extend into a hypertrophied muscularis layer (diverticula in uterine walls)
There are diverticula in the fallopian tube and pregnancy insinuates in these pouches
Salphingitis isthmica nodosa
Independent risk factor for ectopic pregnancy
Smoking
More common
Present with dramatic abdominal pain and vaginal bleeding
High serum B HCG and rapid growth
Higher risk of tubal rupture
Acute Ectopic Pregnancy
Abnormal trophoblast which die early
Negative or low, static serum B HCG
Accumulation of fluid in the cul-de-sac diagnostic surgery
Rupture late
Chronic ectopic pregnancy
Delayed menstruation
Pelvic pain
Vaginal bleeding
Ectopic Pregnancy
Severe pain
Abdominal tenderness
Cervical motion tenderness
Tubal rupture
Pain in the neck or shoulder Hemodynamic changes Vasomotor changes Vertigo Syncope
Hemoperitoneum
Neither intrauterine or extrauterine
Positive for pregnancy but when you do ultrasound, there are no signs of pregnancy
Pain or bleeding but nothing on UTZ
Pregnancy of Unknown Location
ectopic pregnancy because they manifest too early in the pregnancy to be visualized on UTZ
Empty uterus on TVS + bHCG of >3510 mIU/ml
Discriminatory zone
Failed uterine pregnancy
Complete abortion
Ectopic pregnancy
TVS Endometrial findings
Trilaminar endometrial pattern
Anechoic fluid collections
Pseudogestational sac and decidual cyst
Caution advised in diagnosing uterine pregnancy in abscence of a definite yolk sac or embryo
Not all adnexal masses represent ectopic pregnancy
Placental blood flow within the periphery of the complex adnexal mass can aid in diagnosis, but it can also be seen with a corpus luteum of pregnancy
Adnexal findings
Ectopic pregnancy Dx
Laparoscopy
Given to women with ectopic pregnancies who are asymptomatic
Folic acid antagonist
Antimetabolite chemotherapy
Lyses the pregnancy
90% resolution of ectopic tubal pregnancy when given IM
Oral a lot of side effects, not given (stomatitis)
Only effective in DEAD pregnancies or non-viable pregnancies
Methotrexate
Indications for Methotrexate
Unruptured ectopic mass <3.5 cm on UTZ NO FETAL CARDIAC ACTIVITY Asymptomatic Motivated Compliant
Classic predictors of methotrexate success
Low initial serum B HCG
small ectopic pregnancy size
Absent fetal cardiac activity
Single best prognostic factor of successful treatment with single dose methotrexate
Low initial serum B-hCG
Removes unruptured pregnancy <2cm in length and located in the distal third of the fallopian tube
10-15mm linear incision is made on the antimesenteric border over the pregnancy
Salpingostomy
Radical approach
Removing the whole segment of fallopian tube because it is prone to another event of ectopic pregnancy
Salpingectomy
Implant within tbe proximal tubal segment that lies within the muscular uterine wall
Rf: previous ipsilateral salpingectomy
Ruptures late 8-16 weeks gestation due to distensibility of myometrium covering the fallopian tube
Cornual pregnancy
Interstitial pregnancy
Represents on TVS the interstitial portion of the fallopian tube connecting to the uterine cavity and is highly sensitive and specific
Interstitial line sign
Medial to the uterotubal junction and round ligament since the wall is thicker it can be carried to term but with increased risk of abdominal placentation
Angular pregnancy
Spirlberg Criteria to diagnose ovarian pregnancy
Ipsilateral tube intact and distinct from ovary
Ectopic pregnancy occupies the ovary
Ectopic pregnancy is connected by the uteroovarian ligament to the uterus
Ovarian tissue demonstrated histologically
Tx
Wedge resection
Cystectomy
Oophorectomy
Risk factors for ovarian pregnancy
ART
IUD
Cervical pregnancy tx
Methotrexate IM
Hysterectomy
Which of the following sites of tubal pregnancy is known to rupture very early in gestation?
Isthmic