ebola Flashcards

1
Q

when was the first ever case of ebola

A

1976

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2
Q

what is ebola virus formerly called

A

Ebola hemorrhagic fever

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3
Q

what is ebola death percentage of those infected

A

up to 90%

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4
Q

what is the average fatality rate

A

50%

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5
Q

where do most infection occur

A

in sub saharan African

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6
Q

what is it called when a virus effects both animals and humans

A

Zoonotic

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7
Q

where does the name ebola come from

A

the ebola river, situated near the village in the DRC where the first outbreak appeared

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8
Q

what are the initial symptoms

A
headaches 
muscle and joint pain 
loss of appetite 
sore throat 
bleeding or bruising without obvious cause 
abdominal pan
impaired kidney and liver
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9
Q

what are the advanced symtoms

A
blood blisters 
red eyes 
bleeding from the nose and mouth
internal bleeding 
hypotension, multiple organ failure and health
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10
Q

explain the process by which a human may become infected with ebola

A

a person can become infected when encountering an infected animal, such as a fruit bat, monkey, or chimpanzee. The virus’s origin is unknown, but most evidence points to the pteropodidae fruit bat as a key host

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11
Q

explain why it is important for people infected with ebola to be admitted to isolation wards

A

transmission can be through direct contact with an infected person via the skin or mucous. Bodily fluids can include sweat, saliva, faeces, breast milk, semen or urine

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12
Q

define ebola

A

An infectious and frequently fatal disease marked by fever and severe internal bleeding, spreading through contact with infected body fluids by a filovirus (Ebola virus)

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13
Q

describe the spatial distribution of ebola outbreaks

A

to date, local transmission of Ebola in humans has been isolated to the African continent, with outbreaks occurring in the DRC, South Sudan, Uganda, Rupublic of Congo, Guinea, Liberia, Etc

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14
Q

describe the temporal distribution of Ebola outbreaks

A

to date, there have been around 30 human Ebola outbreaks between 1976 and 2021, resulting in more than 300,000 reported clinical cases and 12,630 deaths

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15
Q

explain why less developed countries are more vulnerable to Ebola than more developed countries like the USA

A

Because they often have a wide range of physical and human factors that are not very good. this means that the spread of viruses such as ebola is much more common in less developed countries like west Africa. For example education in West, Africa is limited and therefore they are uneducated on the risk of Ebola and how to prevent it. this directly impacts the spread.

while developed countries like the USA have a good education on ebola and therefore people are aware of the disease and can actively fight it.

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16
Q

explain the human factors that affect the distribution of ebola

A

social behavior- people caring for the sick are likely to become sick

Economy- economy that have been established are more likely to spread through various networks- roads, streets, gatherings

Health system- countries with bad health care will suffer more and lose more lives from ebola

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17
Q

describe how social behavior impacts the distribution of ebola

A

it is only natural for humans to care for the sick, assisting with their cleaning and feeding during a period of illness

Therefore, given that Ebola is transmitted between humans through biological fluids, this rapidly increases the rate of infection within communities.

This also extends to healthcare workers who do not follow correct infection control procedures while treating Ebola patients.

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18
Q

describe how the economy impacts the distribution of ebola

A

As high-risk countries become more economically developed, the spatial impact of ebola can be magnified due to the establishment of road networks, agriculture practices, and large population migration to urban areas.

This causes rapid spread

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19
Q

describe how health systems impact the distribution of ebola

A

lots of west africa have a poor health care system. there is no familiarity for clinical diagnosis, laboratory support for diagnosis was not established, and health facilities were not adequately resourced

as a result of these factors ebola is able to cause more damage to the population, causing more loss of life.

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20
Q

explain the physical factors that affect the distribution of ebola

A

climate- the correlation between location, specifically climate, and the risk of Ebola is high. Different climates can cause worse impacts

geographical location- most outbreaks have been contained to remote rural areas and were controlled rapidly, with support from WHO and other international partners

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21
Q

describe how climate impacts the distribution of ebola

A

It has been observed that hydrologic changes can influence forest fruit production.

Foraging behavior in frugivorous species can be strongly influenced by seasonally driven temporal and spatial clustering of scare fruit resources.

This increases the presence of Ebola as frugivorous species are known to be the main course of ebola

ebola outbreaks are also more likely to occur in times of high absolute humidity, due to increased fruit production and the eating habits of animals that can transmit Ebola becoming more active

in areas of higher rainfall, roads become impassable. It makes it difficult to seek healthcare and implement infection control measures, which directly increases the risk of Ebola transmission.

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22
Q

describe how geographical location impacts the distribution of ebola

A

most outbreaks have been contained in remote rural areas and were controlled rapidly, with support from WHO and other international partners.

the pteropodidae fruit bat is the reservoir host for both human and animal diseases. Thus the spatial distribution of Ebola is influenced by the natural territory of the bat.

through there is uncertainty about which species can transmit Ebola to humans, the fruit bat has been identified as the most likely origin of transmission to humans.

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23
Q

what does WHO stand for

A

world health organization

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24
Q

which countries have been most vulnerable to Ebola outbreaks

A

West Africa due to they perfect geographical location and climate

25
describe the treatment methods of ebola
treatment includes rehydration orally or via intravenous fluids to avoid death from dehydration, which is often caused by diarrhoea. they was also drugs made to act like natural antibodies to prevent a virus from replicating. these treatment drugs were used in conjunction with a vaccination rollout which was approved in 2019
26
how does ebola effect the economy
trade and transportation reduced tourism Decreased agricultural production Decreased mining activity fewer investors higher unemployment
27
how does ebola effect the social aspect
The consequence of ebola might include social unrest, a breakdown in social norms, and disruption in social life. In addition, other services, especially preventive care at the community level can suffer. This exposes entire communities to other health challenges. Another consequence is that people’s social lives are disrupted. For example, funeral processes are sometimes banned and other social activities and festivities restricted.
28
how does the environment effect ebola
The threat of Ebola outbreaks across Africa will increase as levels of greenhouse gases in the atmosphere rise, a raising atmosphere temperature will mean that bats, one of the known causes of the disease will be able to find more food and therefore be more prominent which will lead to more of them getting eaten which in turn leads to more ebola cases
29
where did ebola original start from
it first appeared in 1976 in two simultaneous outbreaks, one in Nzara, Sudan, and the other in Yambuku, Democratic Republic of Congo.
30
how many outbreaks have they been
at least 30 since 1976
31
how many outbreaks occurred in the Democratic Republic of the Congo
12 outbreaks
32
why was the spread of ebola hard to contain in the DRC
at the time of the the outbreak a large amount of armed conflict was occurring in the DRC
33
what was the scale of spatial impact In the DRC
it has covered over 47 health zones across North Kivu and Inure provinces had recorded cases of Ebola
34
what was the initial case of the outbreak in the DRC
it was believed to be an unsafe burial of an infected 65 year old women seven members of her family died shortly after
35
what was the magnitude of the outbreak in DRC
it infected 3,470 people and caused 2287 deaths. The outbreak was officially declared on June 25, 2020
36
what was the duration of this outbreak
it was characterised by the 22 month outbreak period or the typical duration of infection for an individual, which is around two weeks
37
what is the frequency of the ebola outbreak in DRC
high frequency of an ebola occurring DRC has experienced 12 outbreaks since Ebola was first discovered in 1976
38
what caused a higher probability of ebola occurring in DRC
conflict affected a disproportionate number of women, representing two-thirds of cases children were also overrepresented, making up 30 percent of all cases these factors increased the probability of EBola occurring in DRC
39
explain how the conflict in North kiva in the DRC impacted ebola
the impact of increased levels of political unrest and violence has also meant that providing medical support and healthcare has been restricted, therefore intensifying the impacts and number of infections as well as there being security constraints for healthcare workers, which means the typical response for ebola containment, such as contact tracing, is difficult healthcare centers have also been damaged and closed.
40
is their any other diseases in the DRC
it has an ongoing epidemic of measles other diseases that occurs in this area are malaria, yellow fever, typhoid, influenza, and dengue fever
41
what is the role if women in the DRC
the women in DRC usually stay home to cook, clean, and look after sick family members. they often don't take them to get real medical help as it shows a failure on the mother's part to care for the ill. these chances increase the chances of women getting ebola over males
42
cultural practices in DRC
many people that were infected visited traditional practitioners for treatment. these practitioners were not aware of the dangers of ebola and the protective gear that was required traditional burial practices involved cleaning of the decreased, which leads to transmission
43
social impacts of ebola effecting children in DRC
children who lost parents to ebola often became isolated or abandoned. more than 2100 children were orphaned or left unaccompanied because of ebola. lots of schools were closed as they were in high-risk areas. this affected the education of 2 million children. They were also very little education about the viruses and teachers did not have any knowledge to share.
44
social impacts of ebola effecting women in DRC
the women leaders got taught by women from the Collectif de association feminine (CAF)
45
social impacts of ebola effecting political instability in DRC
an estimated 1.2 million people could not vote in the 2018 presidential election in the DRC because of the Ebola outbreak protest, therefore, took place as voters thought ebola was an excuse to exclude them from the vote and influence the election outcome.
46
social impacts of ebola affecting the treatment of health workers in DRC
distrust of contact tracers and healthcare workers caused safety issues as well as the destruction of treatment sites between January to July 2019, there were 198 attacks against healthcare facilities or workers, which significantly increased from the previous six months
47
lessons for COVID-19
because the DRC has outbreaks all the time, there are now common practices that have been put in place to slow the movement of the viruses. these include, contact tracing, isolation, close contacts
48
economic impacts of ebola effecting DRC
ebola has affected the economy of the DRC in several different ways, including ``` less trade and transportation high unemployment reduced terrisum decreased agriculture production decreased mining fewer investors high fiscal impact high unemployment ``` many farmers fled or avoided harvesting due to a fear of transmission, and many house holds reported a loss of income. border closures to avoid the movement of Ebola into other countries can have a significant impact on the country and can make market prices to fluctuate, as they are over 90,000 people crossing the border between Rwanda and DRC each year. The trade between these counties is also valued at around 100 million. Another economic impact is that the WHO only received 50 per cent of its required 140 million funding. being unfunded meant that aid could not be provided at the required standard, resulting in further transmission that could have been prevented.
49
environmental impacts of ebola that occured in the DRC
the western lowland gorilla was impacted by ebola in previous outbreaks. during ebola social dynamics changed, with females transferring from breeding to non-breeding groups. males were observed to move from social groups to become solo these changes impact birth rates as it is estimated to take six years for the social dynamics and population growth to return to pre-ebola outbreak levels we can therefore say that over these 6 years a reduced amount of lowland gorillas were present in the environment and considering their are only around 100,000 of them left it means that this sort of absentence has a big impact on the population.
50
treatment/prevention measures of ebola
treatment for ebola generally looks like supportive care, similar to treatment of covid 19. treatment includes rehydration orally or via intravenous fluids to avoid death from dehydration, which is often caused by diarrhea prevention methods for ebola include hand washing and avoiding physical contact with someone who may be infected with Ebola or the body of someone who died from ebola.
51
mitigation strategy one: vaccinations
there are currently two licenced Ebola vaccines. ervebo was approved for use in November 2019 and can protect those from the zaire Ebolavirus. A second, two dose vaccination was recommended in may 2020 to be delivered, called Zadbeno and Mvabea, for use in anyone aged one year and older. these two doses are delivered eight weeks apart, making them less suitable during an outbreak where immediate protection is needed. agencies have been stockpiling the Ervebo vaccine in preparation for future outbreaks
52
background on the vaccines
the Ervebo vaccine has been administered to more than 350,000 people in both Guinea and the DRC. the vaccination process uses the ring vaccination design. due to covid 19 they is a shortage of vaccines available the vaccination process has gradually improved and adapted to suit the needs of local populations based on cultural beliefs in some regions for example in areas where people feel threated for receiving a vaccine, pop up vaccination sites are set up at health posts instead of near homes of those infected with ebola. more frequently, the WHO has recruited and trained Congolese nationals from Ebola-affected regions to deliver vaccinations. due to the lack of road networks in the DRC authorities are having to utilise other means of transport such as motorcycles and canoes in an effort to treat and vaccinate those with ebola.
53
what is the second approuch to ring strategy
a second approach has been introduced of those at high risk of contracting Ebola. the strategy is called a targeted geographic vaccination where whole villages or neighbourhoods are vaccinated instead of close contacts this strategy successfully prevented an outbreak from spreading to Chow in south Kivu where over 90 per cent of the population who were offered a vaccination accepted it
54
preparedness strategy two: testing and treatment
WHO is heavly involved in supporting countreis that are at high risk of ebola. it works with countries to make preparedness plans and maintain surveillance for Ebola virus cases.
55
what machine is used to collect and test samples of ebola
a GeneXpert machine
56
what training took place in the DRC
laboratory technicians received training from the WHO. the training was on safely collecting and testing samples of possible ebola cases. the benefit of accurate testing facilities means that local provinces and health workers can provide a rapid response this training improved testing facilities meant that over 250,000 contacts were registered, over 220,000 samples were tested, and over 303,000 people were vaccinated during the 2018-2020
57
what were traditional healers trained in
training of traditional healers in order to integrate traditional ways of treating the sick with the skills to identify Ebola and control infection and spread. simples changes such as using protective equipment and protective clothing were difficult to implement but have been important in preparing for future outbreaks traditional healers have been trained in triage so that suspected patients are sent to ebola centers. This accommodation means that possible infected patients can avoid the negative effects of being treated near their home, preventing the risk of infection within the village healers were invited to local health meetings with the officials. they were also trained in reporting deaths or concerns to the relevant authorities for a swift response to limit the spread of ebola.
58
what other preparedness process is suggested
the CDC have suggested early surveillance as a key part of the preparedness plan. survallience includes: monitoring outbreaks in non-human primates, as they often precede ebola ebola outbreaks in humans or coincide. for example, before and during an outbreak in Gabon in 2001, 64 dead antelope, chimpanzee and gorillas were discovered, which was helpful to prepare for the outbreak
59
when did the Ebola virus in the DRC start and end
2018-2020