Early Mobilization Flashcards
Chronic critical illness patients are distinguished by a syndrome of significant, characteristic derangement of: (4)
Metabolism
Neuroendocrine
Neuropsychiatric
Immunologic function
Profound debilitation and continued multiple organ system dysfunction contributes to _____
PMV: prolonged mechanical ventilation
PMV is generally defined as….
The need for mechanical ventilation for LONGER THAN 21 DAYS
OR when the tracheostomy occurs (7-14 days)
Multiple risk factors for post ICU mortality include: (5)
Age Comorbidity Severity of illness Duration of ICU delirium Sepsis
PICS is?
Post intensive care syndrome
PICS is the term used to describe the ________
Constellation of complications that endure past ICU stay
List 6 long term complications of ICU stay
Pulmonary Neuromuscular Physical Function Psychiatric symptoms Cognitive QOL
Pulmonary long term complications include:
Diffusion capacity: generally mild but can persist for >5 years
Long term complications: Neuromuscular include:
CINM, disuse atrophy: can extend to over 5 years, CIP may recover more slowly than CIM
Long term complications: physical function:
ADL dysfunction: may be seen for 1-2 years
Long term complications: Psychiatric symptoms
Depression, PTSD, anxiety
Can persist for over 1 year
Long term complications: Cognitive
Impairments in memory, attention, executive function: residual effects for up to 6 years
Long term complications: QOL
Physical deficits
Improves over 1 year but can persist for over 5 years
ICU-AW stands for
Intensive care unit acquired weakness
_______ is clinically detected weakness in critically ill patients in whom there is no plausible etiology other than critical illness
ICU AW
ICU AW is further classified into _____, _____, or ______
Critical illness myopathy (CIM)
Critical illness polyneuropathy (CIP)
Critical illness neuromyopathy (CINM) Combo of CIP and CIM
Which one of these affects the nervous system? CIP, CIM?
CIP
CIM can be further sub-classified into what 3 categories?
Cachectic myopathy
Thick filament myopathy
Necrotizing myopathy
How do you distinguish between CIP and CIM?
Electrophysiological testing in involved tissues
What develops first? Myopathy or polyneuropathy?
Myopathy- earlier and more frequent
ICU AW is the presence of 1, 2, 5 ; and sometimes either 3 or 4. What are 1, 2 and 5?
- Weakness after onset of critical illness
- Weakness involves prox and distal muscles, symmetrical, flaccid and sparing the CNs. Limbs and resp. Muscles
- Cause of weakness NOT related to underlying critical illness
What can be used in place of MRC when looking at clinical features of ICU AW?
What are the values?
Hand dynamometry
<11 kg force for men
<7 kg force for women
Pathophysiologically important mechanisms for weakness include
Immobility
Local inflammation
Systemic inflammation
What causes pro-inflammatory during critical illness?
Cytokines shift
Increased production of reactive O2 species
Decrease in anti-oxidative defenses
True or false: disuse atrophy and ICU AW are the same?
False
Patients with ICU AW will demonstrate weakness ________ to detectable muscle wasting
PRIOR
Disuse atrophy can demonstrate muscle atrophy and loss of muscle strength by how much percent in the first week?
5%
What is associated with SPECIFIC structural and metabolic changes in muscle?
Disuse atrophy
There is a general shift from _____ fibers to ______ fibers with disuse atrophy
Slow twitch to fast twitch
What is the term that describes the adverse effects on multiple aspects of diaphragmatic structure and function after CMV?
Ventilator induced diaphragmatic dysfunction (VIDD)
As few as ____hours of CMV can result in diaphragmatic atrophy
6-18 hours
_______ will also decrease diaphragm strength by oxidative stress (reactive oxygen species ROS)
Hyperglycemia
Hyperglycemia decreases _____ which is one of the key proteins involved in regulation of cross bridge cycling
Troponin T
Increased ________, decreased ________, and increased ________ causes the muscle atrophy
Increased proteolysis
Decreased protein synthesis
Increased apoptosis
Hypermetabolic stresses of critical illness with result in significant ______ loss in the form of ______
Protein loss
Amino acids
Muscle exhibits a syndrome of _________ where it is unable to use the supply of AA available
Anabolic resistance
Critically ill patients commonly receive less than ___% of their goal nutritional intake during their ICU stay
60%
Bioenergetic failure is reduced ____________ and ATP formation leads to _________ and increased ________
Reduced glucose uptake
Mitochondrial dysfunction
Free radial production
Muscle atrophy occurs with approximately a ____% decrease in muscle fiber area per day with the greatest atrophy in the contractile myosin filaments and relative preservation of other structural proteins.
The muscle protein loss can approach _____% per day
3-4%
2%
ICU AW will affect the ____ and _____ muscles and space the _____ muscles
Limb
Trunk/respiratory
Facial
name some risk factors for ICU AW
Sepsis Multi organ failure Muscle immob HYPERglycemia Corticosteroids Neuromuscular blockers Increased duration or SIRS (systemic inflammatory response syndrome) Mechanical vent for greater than 1 week
Recognized brain dysfunction complicating critical illness and constitutes a major challenge to ICU practioners
Delirium
Characterized by acute disturbances of consciousness accompanied by:
Inattention
Disorganized thinking
Perceptual disturbances that fluctuate over a short period of time
Delirium
Delirium is an important factor in ______time even with light sedation
Ventilation
Three types of delirium:
Hypoactive: lethargy and inattenton
Hyperactive: agitated and combative
Mixed
What does the ABCDE Bundle of Optimal Management consist of?
Awakening and Breathing trial coordination
Choice of sedatives
Daily delirium monitoring
Early mobility and Exercise
Positions that reduce dyspnea:
Upright
Lean forward
Fixation of arms
What is the OPTIMAL position to reduce dyspnea:
Sitting and leaning forward with the arms resting on the thighs
Sitting and leaning forward for COPD patients ______ intra abdominal pressure, causing the curvature of the diaphragm to ______
Increases
Increase
Fixing the arms ______ the load on the diaphragm
Decreases
Safe exercise parameters for HR
Between 40-130 bpm
Safe exercise parameters for RR
Between 5-40 b/min
Safe exercise parameters for SPO2
> 88%
Safe exercise parameters for MAP
Between 65-110 mmHg
Safe exercise parameters for SBP
<200 mmHg
Safe exercise parameters for RPE
Between 10 and 15
Should you do activity with development of arrythmia, angina, or complaint of distress or fatigue?
NOOOOOOOO
Green circle means:
Low risk of adverse event
Yellow triangle means:
Potential risk and consequences of an adverse event are higher than green, but may be outweighed by the potential benefits of mobilization
What does a red octagon mean?
Significant potential risk or consequences of an adverse effect
If percutaneous oxygen saturation is <90%, then….
NO OUT OF BED EXERCISES
Graded mobilization program: Phase 1
Description:
CANNOT FOLLOW SIMPLE DAMANDS
Graded mobilization program: Phase 1
Treatment suggestions
PROM, sitting in chair
3x/day for 20 min
Graded mobilization program: Phase 1
Criteria for next phase
Able to follow simple commands
Graded mobilization program: Phase 2
Description
Follow simple commands, requires max assistance to stand or unable to stand
Graded mobilization program: Phase 2
Treatment suggestions
AA/AROM UE and LE
Bed mobility
Assisted sitting balance activities
Mobile leg press
Graded mobilization program: Phase 2
Criteria for next phase
Requires min-mod assistance to stand and can support majority of BW
Graded mobilization program: Phase 3
Description
Still weak
Requires min to mod assistance
Can support majority or BW
Graded mobilization program: Phase 3
Treatment suggestions
Progress standing with hydraulic assist platform walker
Transfer training to chair
Preaumbulation training with walker
Gait training
Graded mobilization program: Phase 3
Criteria for next phase
Requires min assist to ambulate >10 ft with a walker
Graded mobilization program: Phase 4
Description
Able to transfer and ambulate >10 ft with a walker and min or no assistance
Graded mobilization program: Phase 4
Treatment suggestions
Progressive walking and gait training
High level balance activities
Endurance
Start HEP