E2 Genus Staph & Strep Flashcards
What do Staphylococcus look like?
Buch of grapes
How is Staph differentiated from Strep?
Catalase +
otherwise they look similar
What is are some clinical hallmarks of Staph infection?
Pimple or boil = abscess
Mastitis in cows
What special syndrome can be cause by a Staph infection?
Toxic Shock
What are the coagulase & B-hemolysis of S. aureus?
Coag = + B-Hemo = +
Are Staph commensals and only opportunistic pathogens?
Yes
What is special about some colonies of Staph?
Live in biofilms
What factors of Staph are most important for pathogenesis?
- Protein A = avoids phagocytosis
2. Survives intracellularly in phagocytes
What are some soluble virulence factors?
Leukocidin
Catalase
Coagulase
DNase
What is Toxic Shock Syndrome?
Superantigen activation
Is antibiotic resistance a major problem in Staph?
Yes!
Methicillin Resistance
Use Vancomycin!
What is positive about food animals harboring drug resistant Staph?
Isolates are host-adapted!
What is Staphylococcus hyicus?
Greasy Pig Disease
Esp. piglets
What is Staphylococcus pseudintermedius?
Canine skin infection
Normally commensal
Are Strep bacteria commensals?
Yes!