E2 Genus Brucella Flashcards
What organs do bacteria from the genus Brucella infect?
Reproductive organs
both male and female
What ages are affected by the genus Brucella?
Sexually mature animals
What species of Brucella is not zoonotic?
Brucella ovis
What is species in the most pathogenic in humans?
Brucella melitensis
What is the gram reaction and cultural characteristics of bacteria in the Brucella genus?
- Gram negative small rods
- Aerobic or microaerophilic
- Slow growth
What cells do bacteria in the Brucella genus infect?
- Macrophages
2. Endothelial cells
How does Brucella infect reproductive organs?
Infection of mucous membranes
Bacteremia spread to reproductive organs
How long is the incubation period for Brucella infection?
LONG
1-2 months before clinical signs
What disease do bacteria from the genus Brucella cause in humans?
Undulant fever
What is the disease caused by Brucella abortus in cattle?
Bang’s disease
What is the reservoir for Brucella abortus?
Wild ruminants
What is the prevalence of Brucella abortus in US cattle herds?
Nearly eradicated
What is the most frequent route of infection for Brucella abortus?
GI tract
but can occur through any mucus membrane
When does Brucella abortus cause abortions in cattle?
Late abortions
What effects if any does Brucella abortus have in male cattle?
- Orchitis
2. Epididymitis
How does Brucella abortus affect fertility in male cattle?
Can lead to sterility!
How does Brucella abortus cause abortions in cattle?
- Uldercation of endometrium
2. Destruction of placental villi in cotyledons