dysrhythmia Flashcards

1
Q

Types of triggered activity

A

EAD and DAD

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2
Q

cause of EAD

A

re-activation of L - type calcium channels

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3
Q

cause of DAD

A

overload of intracellular calcium

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4
Q

underlying cause of DAD and EAD

A

SNS
heart failure

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5
Q

cardiac glycosides can cause what type of triggered activity?

A

DAD

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6
Q

blocks of conduction:

A

infarction/ scar

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7
Q

requirements of re-entry

A

slow conduction
uni-directional block

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8
Q

what current underlies phase 4 (pacemaker potential)

A

funny current

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9
Q

phase 0 of pacemaker cells:

A

depolarisation

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10
Q

what ion is responsible for phase 0 of pacemaker potential

A

calcium

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11
Q

what current is responsible for phase 3 of pacemaker potential?

A

delayed rectifier potassium current

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12
Q

class 2 beta receptor antagonists block which current?

A

pacemaker/ funny current

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13
Q

inhibition of which current slows the frequency of electrical activity?

A

funny current

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14
Q

conduction corresponds to which phase of pacemaker AP

A

phase 0 (upstroke)

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15
Q

inhibition of sodium and potassium channels has what effect on electrical activity?

A

slows conduction

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16
Q

how is the refractory period prolonged?

A

inhibition of K channels

17
Q

how is triggered activity reduced?

A

reducing intracellular calcium and L type calcium current

18
Q

what underlies ectopic beats

A

funny current
calcium current
intracellular calcium

19
Q

which tissue do sodium channel blockers act upon?

A

atrial and ventricular

20
Q

which AP phase do sodium channel blockers affect?

A

upstroke (phase 0)

21
Q

which sodium channel blockers prolong the refractory period and AP duration

A

1a by opening K channels

22
Q

what channel state do 1b drugs bind to?

A

inactive

23
Q

which sodium channel blockers have the stronges block?

A

1C