Dyslipidaemia

Question 1

What is dyslipidaemia

Answer 1

Dyslipidaemia is a broad term describing a number of conditions, including
hypercholesterolaemia, hyperlipidaemia and mixed dyslipidaemia, in which
disturbances in fat metabolism lead to changes in the concentrations of lipids in the blood.

Question 2

What are primary and secondary causes of high cholesterol?

Answer 2

Primary: genetic mutations e.g. familial hypercholesterolaemia

Secondary: obesity, DM, hypothyroidism, cholestatic liver disease, drugs e.g. thiazide, atypical antipsychotics

Question 3

What are Sx of hyperlipidaemia

Answer 3

May be

Xanthelasma
Corneal arcus
Xanthomata

Likely none, just presence of risk factors

Question 4

What are risk factors for dyslipidaemia

Answer 4

FH, CVD, fatty diet, abdominal obesity, T2DM

Question 5

What Ix in dyslipidaemia

Answer 5

Lipid profile (cholesterol, triglycerides, LDL, HDL)
TSH
Lipoprotein

Question 6

What are DDx for dyslipidaemia

Answer 6

Obstructive liver disesae
hypothyroidism
nephrotic syndrome

Question 7

What is Rx for dyslipidaemia?

Answer 7

Statins
lifestyle

Ezetimibe

PCSK9 inhibitor