Dunn OB/GYN X Flashcards
amenorrhea
no menses for 3 cycles
17yo F no menses
- cramping monthly with breast tender
- fam hx late menarche
- suprapubic tenderness
- rectal mass
primary amenorrhea
pregnancy test, CBC, US, FSH/LH, E2, karyotype
exam under anesthesia - imperforate hymen**
hematocolpos
retained menstruation by imperforate hymen
female who just reached puberty
tx - cup open
thelarche
onset of female breast development
appearance of sex hair
pubarche
onset of axillary and pubic hair, body odor, acne
adrenarche
onset of menstruation
menarche
tanner stage
1 - prepubertal
to
5 - mature
breast and pubic hair analysis
failure to menstruate by age 16
primary amenorrhea
secondary amenorrhea
absence of menses 3 cycles or >6 months
more common
no secondary sex characteristics
FSH and LH
low -hypogonadotropic gypogonadism
high - karyotype
yes secondary sex characteristics
genetic male or female?
female - mullerian anomaly - no uterus - renal issues as well
male - androgen insensitivity - complete vs. partial
secondary amenorrhea work up
had menstruation, but then stopped
pituitary and thyroid - normal
-then do progestin challenge
causes of primary amenorrhea
constitutional delay
45XO - turner
46XY
pituitary tumor
congenital adrenal hyperplasia**most common cause
second most common cause - Mayer-Rokitansky-Küster-Hauser syndrome
webbed neck, amenorrhea
turner syndrome
45X
Mayer-Rokitansky-Küster-Hauser syndrome
absent uterus
clue to diagnosis of primary amenorrhea
karyotype patient
FSH, LH, PRL levels
headache and visual field defect
pituitary tumor
diagnosis of primary amenorrhea
height, weight, BP secondary sex characteristics look for androgen excess - virilization visual fields chromosomes FSH, LH, E2 hydroxyPROG, androgen, PRL, TSH