Dunn OB/GYN I Flashcards
prenatal care recommendations
office visit at 8-10 weeks of pregnancy
every 4 weeks - first 28 weeks
every 2-3 weeks - 28-36 weeks
every week - after 36 weeks
goal of prenatal care
coordination of care for detected medical and psychosocial risk factor
postpartum care
on or between 21 days and 56 days after delivery
quad screen test
maternal blood screen
AFP
hCG
estriol
inhibinA
AFP
produced by fetus
hCG
produced by placenta
estriol
produced fetus and placenta
inhibin A
produced by placenta and ovaries
decreased AFP and estriol
increased beta-hCG and inhibin A
trisomy 21
ultrasound - nuchal translucency
most likely chromosomal disorder compatible with life
trisomy 21
life expectance 60yo
most common genetic cause of mental retardation
trisomy 21
flat facies, epicanthial folds, duodenal atresia, congenital heart defects, alzheimers and leukemia risk
trisomy 21
decreased AFP, beta-hCG, and estriol
increased inhibin A
trisomy 18
edwards syndrome
trisomy 18
severe mental retardation, rocker bottom feet, micrognathia, low set ears, clenched hands, prominent occiput
trisomy 18
life of trisomy 18
most 5 - 15 days
only 8 % live beyond year
trisomy 13
pataus syndrome
pataus syndrome
US nuchal tranlucency
normal quad scree, possible beta-hCG decreased
trisomy 13
mental retardation, rocker bottom feet, microcephaly, cleft lip, cleft palate, holoprosencephaly, polydactyly
trisomy 13
life of trisomy 13
50% babies live a week
5% live a year
risk of quad screen
no known risks or side effects
when to perform quad screen
16-18 week of pregnancy
-all should be offered
indications:
- family hx
- > 35yo
- harmful med/drug use
- diabetes and insulin **
- viral infection
- exposed high radiation
diabetes and insulin pregnant mother
indication for quad screen
high levels of AFP
suggest neural tube defect
-spina bifida or anencephaly
most common reason for elevated AFP - inaccurate dating of pregnancyf