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pharma 1 > Drugs Used for Treatment of Rheumatoid Arthritis(mechanism) > Flashcards

Drugs Used for Treatment of Rheumatoid Arthritis(mechanism) Flashcards

1
Q

Stabilizes lysosomes and
↓ chemotaxis

A

Hydroxychloroquine

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2
Q

↓ B-cell function

A

Sulfasalazine

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3
Q

Cytotoxic to lymphocytes

A

Methotrexate

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4
Q

↓ LTs, ILs, and platelet activating factor (PAF)

A

Glucocorticoids

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5
Q

Inhibits dihydro-orotic acid dehydrogenase
(DHOD) →↓ UMP(Uridine monophosphate) →↓ ribonucleotides → arrests lymphocytes in G1

A

Leflunomide

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6
Q

Binds tumor necrosis
factor (TNF); is a
recombinant form of TNF
receptor

A

Etanercept

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7
Q

Monoclonal antibody to
TNF

A

Infliximab,
adalimumab

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8
Q

IL-1 receptor antagonist

A

Anakinra

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9
Q

Janus kinase (JAK) inhibitor

A

Tofacitinib

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pharma 1 (13 decks)

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