Drugs That Act On The Kidney

Question 1

What is the main use of diuretics

Answer 1

Oedema

Hypertension

Question 2

How do salts and water move ?

Answer 2

Via pumps channels and osmosis

Question 3

Thiazide and related diuretics 
Example 
Acts on 
Main use 
Works by 
Side effects

Answer 3

Bendroflumethazide and indapamide
Distal convoluted tubule
Oedema - heart failure + LT hypotension
Blocks cl pump ^ excretion of Na and Cl, this ^ k excretion
Hypokalaemia, hypocalcaemia, hypoglycaemia , hyperuricemia

Question 4

Loop diuretics 
Example 
Acts on 
Main use 
 Works by 
Side effects

Answer 4

Furonemiole and bumetonide
A ending loop of helini
Oedema- heart failure or hypotension
Blocks Na/K/Cl pump ^ Na/&/Cl exctection and water follows ^ urine
2 morning and before 4pm
Hypokalaemia, hypocalcaemia, hypoglycaemia , hyperuricemia and deafness

Question 5

ka sparing diuretics 
Example 
Acts on 
Main use 
Works 
Side effects

Answer 5

Spironolactone, eplereone, amiloride 
Late distal tubule and collecting duct
Odeoma hypotension hypokalemia 
^ Na and water exctection and also Cl and ca and decrease in Ka and H
Hypokalaemia, , low Ka

Question 6

Anti diuretics
Works on
Used for
Works by

Answer 6

Collecting lube
Central diabetes insipidus
Vasopressin and desmopressin
Released from posture piturity and it increase the number of Aqua porins which increase passive reabsorption of water

Question 7

What is diuretics?

Answer 7

The increased amount of fluid + salt excreted by kidney