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Clinical Chemistry > Drugs of Abuse > Flashcards

Drugs of Abuse Flashcards

1
Q

Is a psychostimulant and sympathomimetic drug

A

Methampethamine

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2
Q

3 Signs of Opiate Abuse

A

Pinpoint Pupils
Nodding
Withdrawal

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3
Q

Is a crystalline tropane alkaloid that is obtained from the leaves of the coca plant

A

Cocaine

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4
Q

Chemical name for Cocaine

A

Benzomethyl ecgonine

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5
Q

What are the 3 Opiate Receptor

A

µ , Y , ε - receptor

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6
Q

Use to treat the effects of cocaine

A

Tricyclic anti-depressant such imipramine

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7
Q

Drugs of Abuse 5 General Mechanism of Action

A

Opiates , Dopaminergic pathway stimulant , Tranquilizers , Barbiturates ; Sedative/Hypnotic , Hallucinogens

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8
Q

Coexist on inhibitory neurons causing release of GABA at the synapses reducing the dopaminergic effect

A

Diazepam ( Valium) and other Benzodiazepams

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9
Q

2 Major Tranquilizers appear to block attachment of dopamine to the dendritic receptors bloking the stimulatory effects of dopamine

A

Halopredol ( Haldol ) , Chlorpromazine

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10
Q

2 Opiates µ -receptor which produce a general analgesic state

A

Morphine and Heroin

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11
Q

Give 3 example of Drugs which is an Opiate

A

Morphine , Codeine and Heroine

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12
Q

Marijuana is a psychoactive drug extracted from the plant ______

A

Cannabis sativa sub. species indica

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13
Q

The herbal form of the drug are consist of _________ and __________

A

Dried mature flower and subtending leaves of pistillate Female plant

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14
Q

Major biologically active chemical compound in cannabis

A

Δ 9 - Tetrahydrocannabinol

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15
Q

2 intoxiciant form of Marijuana

A

Hashish and Hash oil

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16
Q

A concentrated resin composed of heated glandular trichomes that have been physically extracted, usually by rubbing , sifting or with ice.

A

Hashish

17
Q

Hashish 2 other names

A

Pressed Kief or Charas

18
Q

Marijuana is locally known as

A

Pot, Damo , Jutis, Mary jane and Hash

19
Q

Smoking Devices used in marijuana

A

Screened Bowl , Bongs , Chillums , Paper-wrapped joints and wrapped blunts

20
Q

The minimum amount of THC required to have a perceptible psychoactive effect is about _____ per kilogram of body weight

A

10 µg/kg of body of weight

21
Q

Half life and complete elemination of Marijuana

A

1 week half life and complete elemination 1 month

22
Q

How many percent of unchanged metabolites (THC) are excreted

A
23
Q

Marijuana metabolites undergo ______

A

enterohepatic recirculation

24
Q

True or False . About marijuana 1/3 is excreted in the bile and 2/3 is excreted in the urine

A

False

25
Q

The most common short term physical and neurological effects of marijuana

A

Increase heart rate
Lowered blood pressure
Impairment of psychomotor coordination
Short term memory

Clinical Chemistry (8 decks)

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