Drugs In The CVS

Question 1

Aspirin

Answer 1

• Anti platelet drug (with long term use)
• blocks production of thromboxane
• inhibits enzyme cyclooxygenase which is needed for thromboxane production

Question 2

Prostacyclin

Answer 2

• anti platelet drug
• binds to prostacyclin receptors on platelets
• this increases cAMP and blocks increase of calcium caused by the thromboxane receptor
• blocks platelet aggregation

Question 3

Dipyridamole

Answer 3

• anti platelet drug
• inhibits thromboxane synthetase
• inhibits phosphodiesterase (degreases cAMP)
• blocks platelet aggregation

Question 4

Heparin

Answer 4

• prevents blood clot formation.
• enhances the activity of antithrombin III.
• thrombin is removed from blood so fibrin meshwork isn’t formed.

Question 5

Verapamil

Answer 5

• used to treat high bp
• a Ca++ channel antagonist
• they decrease length of AP
• they decrease contraction Ty of the myocardial cells

Question 6

Diltiazem

Answer 6

• used to treat high bp
• a Ca++ antagonist
• decreases duration of cardiac muscle AP
• decreases strength of contractility of cardiac muscle.