Drugs in Pregnancy Flashcards
What effect does alcohol cause in pregnancy?
Fetal alcohol syndrome
What effect does smoking have in pregnancy?
Low birth weight, preterm birth, cerebral palsy, learning difficult
What effect to drugs (marijuana, ecstacy, cocaine) cause in pregnancy?
Low birth weight, withdrawal symptoms, learning and behavioural problems
What drugs are offered to women experiencing nausea and vomiting?
- Cyclizine (antihistamine)
- Prochloroperazine (phenothiazine)
- Doxtylmaine/pyridoxine comination product
What drugs are given to pregnant people who have hypertension?
- Labetolol, nifedipine, methyldopa, hydralazine
Teratogenic hypertensive drugs?
- ACEi
- ARBs
Safest drugs for epilepsy in pregnacy?
Carbamazepiene and lamotrigene
Always give high dose folic acid
Drugs for diabetes in pregnancy?
- Insulin (safest)
- Gestational diabetes/ type 2 = metformin
Drugs for thromboembolism in pregnancy?
- LMWH (Safe)
- Warfarin (not safe)
Drugs for headaches and migraines in pregnancy?
- Paracetamol
- Ibuprofen (avoid in 3rd tri)
- Sumatriptan (acute treatment)
- Propanolol (lowest effective dose)
Drugs for asthma in pregnancy?
- B2 agonist
- Inhaled costicosteroid
- Systemic corticosteroid (severe asthma)
- Theophyline (potentially toxic)
Are morphine based medicines safe to use in pregnancy?
- No risk of congenital abnormalities
- Risk of neonatal respiratory depression
- Used as labour analgesia
When should codeine be avoided?
During lactation (infant opiate toxicity)
Antidepressants and antipsychotics in pregnanyc?
Weigh risks vs benefits of treatment
Antibiotics in pregnancy?
- Penicillin = safe (check allergies)
- Macrolide = only use if no alternative
- Tetracycline = do not prescribe
- Sulphonamides = teratogenic (avoid in first trimester)
- Aminoglycosides (auditory/vestibular nerve damage)
- Cephalosporins = safe
