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AIM - Heme/Onc > Drugs IDK > Flashcards

Drugs IDK Flashcards

1
Q

cetuximab

A

anti-EGFR

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2
Q

rituximab

A

anti-CD20

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3
Q

eculizumab

A

anti complement C5

PNH

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4
Q

brentuximab vedotin

A

anti-CD30 conjugated to microtubule disrupting agent

“New Directions” for Hodgkins

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5
Q

ipilimumab

A

anti-CTLA4

tumors

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6
Q

nivolumab

A

anti-PD1

Hodgkins

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7
Q

imatinib

A

BCR-ABL inhibitor

CML

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8
Q

erlotinib

A

EGFR inhibitor

lung cancers

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9
Q

ibrutinib

A

bruton’s tyrosine kinase inhibitor

CLL
BTK needed for B cell survival

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10
Q

lenalidomide

A

imid (like thalidomide)

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11
Q

azacytidine

A

demethylating agent

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12
Q

decitabine

A

demethylating agent

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13
Q

aresenic trioxide ATO

A

alternative to ATRA for APL

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14
Q

romiplostim

A

Tpo mimetic

ITP

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15
Q

eltrombopag

A

Tpo mimetic

ITP

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16
Q

prochlorperazine

A 
dopaminergic antagonist
anti emetic (acute/delayed)
17
Q

metoclopramide

A 
dopaminergic antagonist
anti emetic (acute/delayed)
18
Q

epoetin alfa

A
  • ESA
  • short acting epo stimulation
  • pts with chemo
19
Q

darbepoeitin alfa

A
  • ESA
  • long acting epo stimulation
  • pts with chemo
20
Q

filgrastim

A

increases granulocytes (neutrophils)

21
Q

pegfilgrastim

A 
increases granulocytes (neutrophils)
long acting
22
Q

protamine sulfate

A

reversal of heparin anticoagulation

23
Q

allopurinol

A

prevents accumulation of uric acid

tumor lysis syndrome

24
Q

rasburicase

A

turns uric acid into allantoin

tumor lysis syndrome

25
diphenhydramine
counteract extrapyramidal effects of dopamine antagonists
26
fresh frozen plasma
all coagulation factors
27
cryoprecipitate
fibrinogen vWF VIII XIII
28
anti-D immune globulin
against D antigen of Rh complex
29
prothrombin complex concentrates
activated factors - vitamin K antagonists - inhibitors - bleeding disorders
30
albumin
capillary leak syndrome

AIM - Heme/Onc (9 decks)

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