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AIM - Heme/Onc > Drugs IDK > Flashcards

Drugs IDK Flashcards

1
Q

cetuximab

A

anti-EGFR

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2
Q

rituximab

A

anti-CD20

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3
Q

eculizumab

A

anti complement C5

PNH

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4
Q

brentuximab vedotin

A

anti-CD30 conjugated to microtubule disrupting agent

“New Directions” for Hodgkins

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5
Q

ipilimumab

A

anti-CTLA4

tumors

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6
Q

nivolumab

A

anti-PD1

Hodgkins

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7
Q

imatinib

A

BCR-ABL inhibitor

CML

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8
Q

erlotinib

A

EGFR inhibitor

lung cancers

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9
Q

ibrutinib

A

bruton’s tyrosine kinase inhibitor

CLL
BTK needed for B cell survival

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10
Q

lenalidomide

A

imid (like thalidomide)

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11
Q

azacytidine

A

demethylating agent

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12
Q

decitabine

A

demethylating agent

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13
Q

aresenic trioxide ATO

A

alternative to ATRA for APL

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14
Q

romiplostim

A

Tpo mimetic

ITP

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15
Q

eltrombopag

A

Tpo mimetic

ITP

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16
Q

prochlorperazine

A 
dopaminergic antagonist
anti emetic (acute/delayed)
17
Q

metoclopramide

A 
dopaminergic antagonist
anti emetic (acute/delayed)
18
Q

epoetin alfa

A
  • ESA
  • short acting epo stimulation
  • pts with chemo
19
Q

darbepoeitin alfa

A
  • ESA
  • long acting epo stimulation
  • pts with chemo
20
Q

filgrastim

A

increases granulocytes (neutrophils)

21
Q

pegfilgrastim

A 
increases granulocytes (neutrophils)
long acting
22
Q

protamine sulfate

A

reversal of heparin anticoagulation

23
Q

allopurinol

A

prevents accumulation of uric acid

tumor lysis syndrome

24
Q

rasburicase

A

turns uric acid into allantoin

tumor lysis syndrome

25
Q

diphenhydramine

A

counteract extrapyramidal effects of dopamine antagonists

26
Q

fresh frozen plasma

A

all coagulation factors

27
Q

cryoprecipitate

A

fibrinogen
vWF
VIII
XIII

28
Q

anti-D immune globulin

A

against D antigen of Rh complex

29
Q

prothrombin complex concentrates

A

activated factors

  • vitamin K antagonists
  • inhibitors
  • bleeding disorders
30
Q

albumin

A

capillary leak syndrome

AIM - Heme/Onc (9 decks)

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