Drugs for Thromboembolic Disorders Flashcards
1
Q
Clopidogrel MOA
Use:
A
Prevent ADP binding to P2Y
Stent placement
2
Q
Abciximab MOA
Use:
A
Fab fragment that binds GpIIb/IIIa and inhibits aggregation
Acute coronary syndromes
3
Q
Cilostazol MOA
Use:
A
Inhibit PDE-3
Claudication
4
Q
Dipyramidole MOA
Use:
A
Inhibit PDE-3
TIA prevention
5
Q
Heparin, Enoxaparin MOA
A
Indirectly inhibit factor Xa and thrombin
Given parenterally
6
Q
Fondaparinux MOA
A
Indirectly inhibit Xa
Given parenterally
Does not cause heparin-induced thrombocytopenia
7
Q
Rivaroxaban MOA
Use:
A
Directly bind and inhibit factor Xa
Prevent PE and DVT
Used orally
8
Q
Bivalirudin, Argatroban MOA
A
Directly inhibit thrombin
Prophylactic Tx
Given parenterally
9
Q
Dabigitran MOA
A
Directly inhibit thrombin
Reversible
Given orally
