Drugs and usual doses Flashcards

1
Q

Schedule for Percocet

A

II- high potential for abuse

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2
Q

Schedule for Vicodin

A

III- moderate potential for abuse

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3
Q

Schedule for Tylenol #3

A

III moderate potential for abuse

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4
Q

Schedule for Darvocet

A

IV low potential for abuse

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5
Q

Percocet 5/325?

A

oxycodone/ acetaminopen 5mg/325mg QID

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6
Q

Roxicet?

A

Oxycodone/acetaminopen

  • 5mg/325mg/ 5mL
  • essentially a liquid form of Percocet that is good for pediatric patients
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7
Q

What is the difference between Percocet and Percodan?

A
  • Percocet has 325 acetaminophen

- Percodan haas 325 mg of ASA

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8
Q

Vicodin 5/500

A

hydrocodone/acetaminophen 5mg/500mg

QID

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9
Q

Tylenol #3

A

codeine/acetaminophen 30mg/300mg

QID

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10
Q

Darvocet N100

A

propoxyphene/acetaminophen
-100mg/650mg

q4

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11
Q

Ultram

A

Tramadol 50mg

QID

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12
Q

Toradol

A

Ketorolac 10mg

-an NSAID that should not be used more than 5 days due to possible significant side effects

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13
Q

Darvon

A

-propoxyphene

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14
Q

OxyContin

A

oxycodone extended release

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15
Q

Morphine sulfate

A

2-4mg IV QID.

-usually used for very painful dressing changes or bedside debridement

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16
Q

MS Contin

A

morphine sulfate extended release 15-30mg

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17
Q

Dilaudid

A

hydromorphone

Very strong drug

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18
Q

What are the therapeutic effects seen with acetaminophen (2)

A

analgesic and anti-pyretic

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19
Q

What is the maximum daily dose of acetaminophen

A

4grams

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20
Q

What therapeutic effects are seen with most NSAIDS (3)

A

analgesic, anti-pyretic, anti-inflammatory

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21
Q

What pathway do NSAIDS work on

A

cyclooxygenase

NSAIDS nonselectively inhibit both COX-1 and COX-2

22
Q

What is the most common side effect of NSAIDs

A

GI disturbance ( especially if it is a strong COX-1 inhibitor)

23
Q

What is the only FDA approved COX-2 inhibitor

A

celecoxib

-others were withdrawn due to increased risk of heart attack and stroke

24
Q

Which NSAIDS only have anti-inflammatory effects

A

Indomethacin and tolmetin

25
Q

Do NSAIDs decrease joint destruction

A

no they only decrease inflammation

26
Q

Do NSAIDs affect bone healing

A

NSAIDs and COX-2 inhibitors may inhibit bone healing via their anti-inflammatory effects

27
Q

What NSAID causes irreversible inhibition of platelet aggregation

A

aspirin

28
Q

What NSAID does not inhibit platelet aggregation

A

the COX-2 inhibitor celebrex

29
Q

What is the only IV NSAID

A

ketorolac (toradol)

30
Q

What NSAID is often given during surgery or immediately post-op to decrease pain and inflammation

A

-Toradol 30mg IV

31
Q

What are the NSAIDs with the least neprotoxicity

A
  • celebrex
  • Relafen
  • Lodine
32
Q

What is the effect of NSAIDs for a patient with asthma

A
  • can increase the symptoms of asthma
33
Q

What are the safest NSAIDs for a patient with asthma

A

and ketoprofen

34
Q

Which NSAIDs treat collagen vascular disease

A

ibuprofen, sulindac, tolmetin

35
Q

Which NSAIDs are not renally cleared

A

indomethacin and sulindac

36
Q

What are the cardiovascular effects of NSAIDS

A

they can cause vasoconstriction and increase blood pressure

37
Q

Which NSAIDs have the least cardiovascular effects

A

diclofenac and ketoprofen

38
Q

Which NSAIDs are the most hepatotoxic

A

Ibuprofen, naproxen and diclofenac

39
Q

What should be given for an indomethacin overdose

A

benadryl

-decreaes serotonin and histamine release

40
Q

What is arthrotec

A

diclofenac and misoprostol

-an NSAID with protection for the stomach

41
Q

What is the anti-inflammatory dose of ibuprofen

A

1200-3200 mg/day in divided doses

42
Q

What NSAIDs work on both the lipooxygenase and cyclooxygenase pathways

A

-ketoprofen and diclofenac

43
Q

What is the difference between Cataflam and Voltaren

A
  • Cataflam is diclofenac potassium and has in immediate release
  • Voltaren is diclofenac sodium and has a delayed release
44
Q

What are the only pro-drugs for NSAIDs

A

nabumetone and sulindac

45
Q

What is the only nonacidic NSAID

A

nabumetone

46
Q

Which NSAIDs have fewer pulmonary problems

A

ketoprofen and diclofenac

47
Q

What are the 6 classification types of NSAIDs

A
  • Salicylic acid derivatives
  • Propionic acid
  • Acetic acid
  • Fenamates
  • Enolic/-oxicams
  • Cox2 inhibitors
48
Q

What are the salicylic acid medications (4)

A
  • ASA
  • diflunisal
  • salsalate
  • Trilisate
49
Q

What are the propionic acid medications (5)

A
  • flurbiprofen
  • ibuprofen
  • ketoprofen
  • naproxen
  • oxaprozin
50
Q

What are the acetic acid medications (7)

A
  • diclofenac
  • etodolac
  • indomethacin
  • ketorolac
  • nabumetone
  • sulindac
  • tolmetin
51
Q

Enolic acid/ oxicams (2)

A

meloxicam and piroxicam

52
Q

Cox-2 inhibitors

A

celecoxib