Drugs and motility in the GI tract - Emetics Flashcards
1)receptor 2)location of action 3) actions
1
Q
what is the function of emetics?
A
to stimulate nausea and vomitng
2
Q
Give two examples of emetics
A
Ipecacuanha
Apomorphine
3
Q
What are the active constituents of Ipecacuanha?
A
The active constituents are the alkaloids emetine and cephaline
4
Q
Where does Ipecacuanha act?
A
The stomach lining
5
Q
What is the action of Ipecacuanha?
A
irritant of stomach lining leading to vomiting
6
Q
At what receptor does Apomorphine act?
A
D2 receptor agonist
7
Q
Where in the brain does Apomorphine act?
A
acts centrally in the Chemical trigger zone
8
Q
What is the mechanism of action of Apomorphine?
A
leads to stimulation of the vomiting centre leading to vomiting
