Gastric Ulceration - Antacids

Question 1

Sodium Bicarbonate (NaHCO3)
soluble fast acting drug

Answer 1

1) the sodium bicarbonate reacts with HCl to produce NaCl and H2CO3.
H2CO3 then breaks down to CO2 + H2O
2) direct neutralisation in stomach
3) CO2 production may cause discomfort

Question 2

Magnesium hydroxide or Magnesium trisilicate

Answer 2

1) Magnesium hydroxide or Magnesium trisilicate
react with HCl to form insoluble colloid MgCl2 and H2O or silica.
2) direct neutralisation in stomach
3) Diarrhoea

Question 3

aluminium hydroxide gel

Answer 3

1) aluminium hydroxide gel reacts with HCl to produce the insoluble colloid AlCl2
2) direct neutralisation in stomach
3) Constipation