Drugs and Heart Failure - KAHOOT Flashcards

1
Q

Increased permeability to which ion induces the action potential in a nerve fibre ?

  • Calcium
  • Sodium
  • Potassium
  • Magnesium
A
  • Sodium
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2
Q

Which of the following drugs would you use to treat sinus bradycardia?

  • Amiodarone
  • Digoxin
  • Lidocane
  • Atropine
A

Atropine

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3
Q

The “use dependency” of anti-arrhythmic drugs is due to the selective effect on ….?

  • Channel type
  • Channel State
  • Multiple types of channel
  • Conduction through thr AV node
A
  • Channel State
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4
Q

Which mechanism explains the positive inotropic action of digoxin?

  • Inhibatition of NA/K ATP-ASE
  • inhibition of NA/CA exchange
  • Inhibition of NA/K/2CL syporter
  • Enhances parasympathetic nerve activity.
A
  • Inhibition of NA/k ATPASE
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5
Q

When is digoxin used ?

A

A- fib
or HF

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6
Q

Which drug does not reduce mortality in chronic heart failure ?

  • B adrenoreceptor antagonist
  • ACE inhibitor
  • Loop diuretic
  • Angiotensin receptor antagonist
A
  • Loop diuretic
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7
Q

Which adverse effect would be most likley following the use of loop diuretic furosemide ?

  • Breast pain
  • Deafness
  • Hyperkalemia
    -Peripheral oedema
A
  • deafness
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8
Q

Which anti-arrhythmic group would be most effective in treating arrhythmia due to hyperthyroidism?

  • Potassium Channel blocker
  • Beta Blocker
  • Sodium Channel Blocker
  • Calcium Channel Blocker
A
  • B Blocker
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9
Q

Which calcium antagonist would be most effective in treating supraventricular tachycardia?

  • Verapmil
  • Nifedipine
  • Amlodipine
  • Diltiazem
A

Verapamil

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10
Q

Which of the following anti-arrythmic properties is not possessed by amiodarone ?

  • Sodium Channel Blockage
  • Calcium Channel Blockage
  • Na/K ATPase inhibition
  • Pottasium Channel Blockage
A

NA/K ATPase Inhibition

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11
Q

Why may digoxin be a usefull drug in treating a supraventricular tachycardia ?

  • Enhances Sympathetic Transmission at the SA node
  • Enhances parasympathetic transmission at the AV node
  • Induced complete heart block
  • Inhibits ventricular fibrilliation
A
  • Enhances parasympathetic transmission at the AV node
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12
Q

Which of the following is NOT a significant adverese effect of amiodarone?

  • Deposit microcrystals in the eye
  • Tordes des pointes
  • Lung Fibrosis
  • Diabetes
A

Diabetes

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13
Q

Which drug mechanism reduces hospitalisation, but not survival in chronic heart failure?

  • Aldosterone antagonist
  • ACE inhibitor
  • NA/K ATP-ase Inhibitor
  • B-adrenoceptor antagonist
A
  • Na/K ATP- ase Inhibator
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14
Q

Which drug group can initially reduce cardiac output but decrease mortality in chronic heart failure?

  • aldosterone antagonist
  • B-adrenoceptor antagonist
  • ACE inhibitors
  • Angiotensin II receptor antagonist
A
  • B - adrenoceptor antagonist
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15
Q

In which combincation are all drugs used to treat cardiac arrhytmias ?

  • Nitrates/CCB/B- Blockers
  • ACE Inhibitors/thiazide diuretics/CCB
  • Loop Diuretics/ACE inhibitors/ Digoxin
  • B-Blockers/Digoxin/Potassium Channel blockers
A

B-Blockers/Digoxin/Potassium Channel blockers

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16
Q

Which drug is used to treat the oedema associated with heart failure ?

  • Asprin
  • Furosemide
  • Atrovastatin
  • Alteplase
A
  • Furosemide