Drugs and Clinical Care Flashcards

1
Q

What are common tx malpractice

A
  1. Steroids
  2. beta blockers
  3. miotics
  4. oral carbonic anhydrase inhibitors
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2
Q

What are common tx negligence in order from most common to least common

A
  1. Failure to diagnose
  2. Delayed diagnosis
  3. Misdiagnosis
  4. Improper management
  5. Failed/delayed referral/consultation
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3
Q

Schedule ____ refers to high abuse, no known medical use, lack of safety

A

I; heroin

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4
Q

Schedule ____ refers to high abuse, some medical use, high risk of dependency

A

II; hydrocodone

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5
Q

Schedule _____ refers to lower abuse, medical use, and moderate dependency risk

A

III; valium

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6
Q

Schedule ____ refers to limited abuse, high medical use, limited dependency risk

A

IV; codeine

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7
Q

Schedule ____ refers to minor problems; may be available without rx

A

V; penicillin

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8
Q

Category ___ means there is no evidence of risk in women. Category ___ means there is no evidence of risk in animals. Category ___ means animal toxicity is evident. Category ____ means risks may outweigh benefits. Category ___ means risks are greater than benefits

A

A; B; C; D; X

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9
Q

What is anaphylaxis

A

A systemic hypersensitivity reaction with a substance to which the body has been previously sensitized

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10
Q

T/F Any physician may prescribe drugs off label

A

T

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11
Q

T/F There is no FDA drug approved to treat ulcers

A

T

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12
Q

FDA requires a minimum of ___% drug activity and a > ____ month shelf life

A

90; 18

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13
Q

What are various methods for delivery of drugs to the anterior and posterior chambers of the eye?

A
  1. Eye drops
  2. Scleral plug
  3. Subconjunctival implant
  4. Suprachoroidal implant
  5. Suprascleral injection
  6. Suprascleral injection
  7. Intravitreal implant
  8. Intravitreal injection
  9. Oculuex products
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14
Q

What are the most common ophthalmic drug formulations

A

solution

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15
Q

What drug formulation must be shaken

A

suspension

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16
Q

What are the drug formulations

A
  1. gel
  2. ointment
  3. solids
  4. solution
  5. suspension
  6. colloid
  7. sprays
17
Q

what are the different types of solids

A
  1. contact lenses
  2. collagen shields
  3. filter strips
  4. cotton pledets
  5. lacrisert
  6. vitrasert
  7. lucentis
18
Q

Exipients/vehicles are inert and lack all elements of a preparation other than the active ingredient and the _____

A

preservative

19
Q

What are the different excipients

A
  1. Emollient: mineral oil
  2. Emulsifier
  3. Demulcent
  4. Buffers
20
Q

____ soothe the skin and support the drug but they themselves don’t provide therapeutic benefit, and ____ soothe mucous membrane

A

Emollient; demulcents

21
Q

____ keep solids in liquids well dispersed

A

emulsifiers

22
Q

What are the drug vehicles

A
  1. viscosity enhancer
  2. osmoprotectant
  3. stabilizers
  4. tonicity stabilization
23
Q

what are the different kind of preservatives

A
  1. chelators
  2. chemical toxins
  3. surfactants
  4. disappearing oxidants
  5. EDTA
24
Q

_____ are substances that have affinity that bind for metallic ions by combining metallic ions that are cofactors for enzymes and disable microorganisms key enzymes that are essential for life function

A

chelators

25
Q

What are the different types of chemical toxin preservatives

A
  1. alcohol
  2. heavy metals
  3. bacteriostatic
26
Q

Surfactants can be ____ or bacteriocidal

A

ionic

27
Q

____ is a chemical toxin that was once used as a blood substitute

A

PVP (Povidone)

28
Q

What are the two preservative surfactants

A
  1. Biguanides

2. Quaternary ammonium compounds

29
Q

What are the differernt biguanides

A
  1. PHMB
  2. PAPB (Dymed)
  3. Chlorhexidine
  4. Alexidine
30
Q

What are the quaternary ammonium compounds

A
  1. BAK

2. Quats

31
Q

The most common preservative used in topical ophthalmic drops is

A

BAK

32
Q

What are the two disappearing oxidants

A
  1. Borate complexes (pH inactivated)

2. Chlorite complexes (light inactivated)

33
Q

What are the preservative free drops

A
  1. various artificial tears
  2. cyclosporine
  3. timolol
  4. zioptan
  5. ketorolac
  6. cosopt PF
34
Q

What are the self preserved drops

A

moxifloxacin