Anasthetics Flashcards

1
Q

What are the PABA esters

A
  1. Tetracaine
  2. Benzocaine
  3. Benoxinate
  4. Procaine
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2
Q

What are the MABA esters

A
  1. Proparacaine
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3
Q

What is the BA ester

A

cocaine

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4
Q

What are the amides

A

(LMBEP)

  1. Lidocaine
  2. Mepivicaine
  3. Bupivicaine
  4. Etidocaine
  5. Prilocaine
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5
Q

How are amides metabolized and what order metabolism

A

by the liver; 0 order

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6
Q

Which ester has the least corneal compromise

A

benoxinate

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7
Q

which ester has the greatest corneal toxicity and penetration

A

tetracaine

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8
Q

what is the onset of topical esters and what is the duration

A

0.5 min (30 sec) and duration is 1/4 of an hour

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9
Q

what is the onset of lidocaine and what is its duration

A

4-6 min and duration is 2/3- 1 hour

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10
Q

Toxicity is ____ related to dose

A

exponentially

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11
Q

____ show high allergy potential

A

Esters

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12
Q

Esters based anesthetics are category C for pregnancy, lidocaine topical is category ____ for pregnancy

A

B

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13
Q

What are injectable non anesthetic alternatives

A
  1. antihistaminics

2. saline

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14
Q

what are topical non anesthetic alternatives

A

antihistaminics

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15
Q

what are the classic vasoconstrictors

A

phenylephrine and epinephrine

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16
Q

what are advantages of phenylephrine and epinephrine

A
  1. reduce absorption/systemic toxicity
  2. reduce metabolism
  3. sustain local effect
  4. reduce bleeding at injection site
17
Q

What are adverse ocular effects of cocaine

A
  1. epithelial desquamation
  2. mydriasis
  3. lid retraction
18
Q

what are drug interactions with topical cocaine

A
  1. TCADS
  2. MAO inhibitors
  3. Decongestants
  4. Antihypertensives