Drugs Acting on the Endocrine System

Question 1

Drugs for hypothalamus, pituitary, thyroid, and parathyroid glands

Answer 1

Hypothalamic Agents
Pituitary Agents
Thyroid Agents
Antithyroid Agents
Parathyroid Agents

Question 2

Drugs for adrenal gland and pancreatic disorders

Answer 2

Antidiabetic Agents
Glucose-elevating Agents

Question 3

The adrenocortical drugs and mineralocorticoid drugs

Answer 3

Adrenocortical Agents
Mineralocorticoid Agents

Question 4

Drugs Affecting the Thyroid and Parathyroid Glands

Answer 4

Thyroid Agents
Antithyroid Agents
Parathyroid Agents

Question 5

these synthetic or natural hormones replace the low or absent levels of natural thyroid hormones and influence organs and tissues. These hormones
are concerned with increasing the metabolic rate of tissues, resulting to increase oxygen consumption, respiration, heart rate, growth and maturation, and increase in the metabolism of fats, carbohydrates, and proteins.

Answer 5

Thyroid Agents

Question 6

these agents are used as replacement hormone for hypothyroid states (myxedema coma, Hashimoto’s disease, thyroid cancer); suppression of
TSH in euthyroid goiter; treatment for thyroid toxicity in conjunction with antithyroid drugs; treatment for thyroid overstimulation during pregnancy; diagnostic drug to differentiate suspected hyperthyroidism from euthyroidism

Answer 6

Thyroid Agents

Question 7

Adverse effects: skin rashes, hair loss, symptoms of hyperthyroidism (heat intolerance, elevated blood pressure, tachycardia, diaphoresis, tremors, insomnia, anxiety, fatigue, weight loss, flushing)

Answer 7

Thyroid Agents

Question 8

Diseases/Illness that thyroid agents are contraindicated

Answer 8

cardiovascular disorders
adrenal insufficiency

Question 9

Which drug decrease the absorption of thyroid hormones?

Answer 9

cholestyramine

Question 10

Which drugs leads to decreased effectiveness of cardiac drugs when it interacts with thyroid agents?

Answer 10

digoxin
beta-blockers

Question 11

thyroid agents increase risk of hypoglycemia when it interacts with…

Answer 11

insulin and oral hypoglycemics

Question 12

thyroid agents increase risk for bleeding when it interacts with…

Answer 12

oral anticoagulants

Question 13

effectiveness of thyroid agents decreases when it interacts with…

Answer 13

antidepressants

Question 14

Patients teachings to clients who takes thyroid agents:

Answer 14

• adhere to blood test schedule
• maintain proper skin care
• adhere to follow-up check -up and blood test schedules

Question 15

acts to suppress the production of thyroid hormones. They do not affect existing thyroid hormones that are circulating in the blood or stored in the thyroid gland.

Answer 15

Antithyroid Agents

Question 16

Indication: diagnosis and treatment of hyperthyroidism; suppression of thyroid function before surgery for hyperthyroidism; treatment of Grave’s disease, thyroid crisis

Answer 16

Antithyroid Agents

Question 17

two subcategories of antithyroid agents

Answer 17

Thioamides
Iodine Solutions

Question 18

these agents prevent the synthesis of thyroid hormone in the cells,
thus lowering the serum levels of thyroid hormone. They also partially inhibit
the conversion of T4 to T3 at the cellular level.

Answer 18

Thioamides

Question 19

Adverse effects: symptoms of thyroid suppression (drowsiness, lethargy,
bradycardia, weight gain); GI symptoms (nausea, vomiting); paresthesias

Answer 19

Thioamides

Question 20

creates an oversupply of iodine causing the thyroid cells to stop
producing hormones. In some cases, these agents (e.g. radioactive iodine)
can cause thyroid cell destruction

Answer 20

Iodine Solutions

Question 21

Adverse effects: hypothyroidism, iodism, teeth staining, skin rashes, goiter,
nausea, vomiting, tachycardia

Answer 21

Iodine Solutions