Drugs Flashcards

Case 3 drugs

1
Q

What is Clarithromycin

A

antibiotic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is amoxicillin

A

antibiotic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

How does a nicotine replacement theory do its thing ( Varenicline )

A

reduces nicotine craving

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the mechanism of action of Varenicline

A

Partial agonist of α4ß2 nicotinic Ach receptor. It stimulates the nicotinic receptors more weakly than nicotine itself. It reduces the downstream release of dopamine.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Mechanism of action of Clarithromycin

A

Penetrates bacterial cell wall and reversibly binds to domain V of 23s ribosomal RNA of the 50s ribosome thus blocking polypeptide synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Mechanism of action of Amoxicillin

A

Binds to penicillin-binding protein 1A located in cell wall of bacteria. Inactivation of enzyme prevents the last stage of bacterial wall synthesis and cell lysis is then mediated by bacterial cell wall enzymes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly