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Cardio > Drugs > Flashcards

Drugs Flashcards

1
Q

What class of drug is abciximab?

A

Glycoprotein IIb/IIIa receptor

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2
Q

What class of drug is eptifibatide?

A

Glycoprotein IIb/IIIa receptor

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3
Q

What class of drug is tirofiban?

A

Glycoprotein IIb/IIIa receptor

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4
Q

Side effect of clopidogrel?

A

Skin rash

Other SEs: diarrhoea, abdominal pain, dyspepsia

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5
Q

Side effect of aspirin?

A

Can precepitate bronchospasm (up to 20% of asthmatic adults)

Gastric side effects: nausea to major GI bleeds

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6
Q

Contraindications to ACEi?

A 
Aortic/mitral valve stenosis
Angioedema
Hypersensitivity to ACEis
Bilateral renal artery stenosis
Pregnancy
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7
Q

ACEi monitoring?

A

Baseline BP, urea and electrolytes before starting.
Check BP and U&E’s within 2 weeks of starting/changing dose
Then check BP and U&E’s annually

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8
Q

Side effects of ACEi?

A

First-dose hypotension (avoid excessive diuretics prior to initiation)
Dry cough
Andioedema (rare but potentially life-threatening adverse effect)
Rash

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9
Q

Contraindications to beta-blockers?

A

Asthma
Second or third degree heart block
Severe peripheral vascular disease
Patients on verapamil

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10
Q

Adverse effects of CCBs?

A 
Bradycardia
Hypotension
Flushing (gets better with time)
GI disturbance - may make constipation worse
Ankle oedema
Gingival hyperplasia
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11
Q

Side effects of statins?

A

Gi disturbance
Insomnia
Muscle aches and pains, myopathy

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12
Q

Adverse effects of nitrates?

A

Hypotension

Headache

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13
Q

How does nicorandil work?

A

Potassium channel activator

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14
Q

Adverse effects of potassium channel activators?

A

Headache
Dizziness and hypotension
Fludhing
ULCERATION - GI ulceration, skin ulceration, ulceration of the mucosal membranes

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15
Q

Adverse effects of ivabradine

A 
Visual symptoms (luminous phenomena, blurred vision)
Bradycardia/ AV 1st degree block
Headache
Dizziness
GI disturbances
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16
Q

Side effect of hydralazine

A

Drug-induced lupus

17
Q

Beta-blockers that improve survival in heart failure?

A

Bisoprolol, carvedilol, nebivolol

18
Q

When would you give digoxin in heart failure?

A

If symptoms persist despite ACEi, betablocker and aldosterone antagonist
-particularly useful if patient has AF as well!!

19
Q

Vaccines to offer in heart failure

A
  • once off pneumococcal

- annual flu vaccine

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