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Cardio > Drugs > Flashcards

Drugs Flashcards

1
Q

How does aspirin work?

A

Antiplatelet - inhibits production of thromboxane A2

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2
Q

How does clopidogrel work?

A

Antiplatelet - inhibits ADP binding to its platelet receptor

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3
Q

How does enoxaparin work?

A

Inhibits factor Xa

Activates anti-thrombin III, which potentiates inhibition of coagulation factor Xa

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4
Q

How does fondaparinux work?

A

Inhibits factor Xa

Activates antithrombin III which potentiates inhibition of coagulation factors Xa

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5
Q

How does Bilvalirudin work?

A

Reversible direct thrombin inhibitor

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6
Q

How does abciximab work?

A

Glycoprotein IIb/IIIa receptor antagonist

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7
Q

How does eptifibatide work?

A

Glycoprotein IIb/IIIa receptor antagonist

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8
Q

How does tirofiban work?

A

Glycoprotein IIb/IIIa receptor antagonist

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9
Q

Activates antithrombin III which potentiates inhibition of coagulation factors Xa

A

Enoxaparin, fondaparinux

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10
Q

Amiodarone dose

A

300mg

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11
Q

Adenosine dose

A

6mg

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12
Q

Atropine dose

A

300 micrograms

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13
Q

Bosentan mechanism of action?

A

Endothelin receptor antagonist

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14
Q

What condition would you use bosentan in?

A

Primary pulmonary hypertension

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15
Q

Which beta-blocker can cause long QT?

A

Sotalol

Tricyclics, SSRIs (citalopram), haloperidol also

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16
Q

Which drugs can cause long QT?

A

Sotalol

Tricyclics, SSRIs (citalopram), haloperidol

17
Q

Main action of amiodarone?

A

Blocks potassium channels

18
Q

Drug treatment for native valve endocarditis?

A

Amoxicillin and gentamicin

19
Q

Drug treatment for native valve endocarditis with severe sepsis, penicillin allergy or suspected MRSA

A

Vancomycin and gentamicin

20
Q

Drug treatment for native valve with severe sepsis and risk factors for gram negative infection

A

Vancomycin and meropenem

21
Q

Prosthetic valve endocarditis?

A

Really Good Valve

Rifampicin, gentamicin, vancomycin

22
Q

Alteplase mechanism of action

A

Activates plasminogen to form plasmin

23
Q

How do statins work?

A

Inhibit HMG-CoA reductase, the rate limiting enzyme in hepatic cholesterol synthesis

24
Q

Which beta blockers have been shown to reduce mortality in stable heart failure?

A

Bisoprolol and carvedilol

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