drugs

Question 1

ethosuximide

Answer 1

anticonvulsant (epilepsy) for petit mal

Question 2

diazepam

Answer 2

anticonvulsant (epilepsy)

increases GABA action at GABAa receptors + increases frequency of opening

Question 3

clozapine

Answer 3

neuroleptic (schizophrenia)

blocks D2 receptors in mesolimbic pathway

Question 4

clonidine

Answer 4

alpha 2 agonist

vasoconstriction

Question 5

carbamazepine

Answer 5

anticonvulsant (epilepsy) - grand Mal

reduces Na+ conductance = inhibition of high frequency action potentials

also used for manic depression

Question 6

acetozolamide

Answer 6

carbonic anhydrase inhibitor

at DCT, PCT, collecting duct

less H+ excretion via H+/Na+ antiport
therefore less Na+ reabsorption
less water reabsorption

Question 7

amiloride

Answer 7

potassium sparing diuretic

at DCT, Collecting duct
blocks Na+ reabsorption

Question 8

triamterene

Answer 8

potassium sparing diuretic

at DCT, collecting duct
blocks Na+ reabsorption

Question 9

amitriptyline

Answer 9

TCA antidepressant

blocks 5-HT and NA reuptake

also blocks muscarinic, alpha adreceptors and H1 receptors.

Question 10

atropine

Answer 10

muscarinic antagonist

decreases vagal stimulation
used before surgery

Question 11

benzhexol

Answer 11

muscarinic antagonist

parkinsons

Question 12

bupivacaine

Answer 12

local anaesthetic

amide

Question 13

chlorpomazine

Answer 13

neuroleptic (schizophrenia)

blocks D2 receptors in mesolimbic pathway
also blocks alpha adrenoceptors = hypotension

Question 14

dobutamine

Answer 14

beta 1 agonist

Question 15

dorzolamide

Answer 15

carbonic anhydrase inhibitor - topical

Question 16

brinzolamide

Answer 16

carbonic anhydrase inhibitor - topical

Question 17

dyflos

Answer 17

irreversible acetylcholinesterase inhibitor

binds to serine site

Question 18

entacapone

Answer 18

COMT inhibitor - short acting