Drugs Flashcards

1
Q

Griseofulvin MOA

A

MT inhibitor

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2
Q

5-FU MAO

A

Inhibits DNA/RNA synthesis

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3
Q

Polyenes MAO & ex

A

Bind ergosterol & form pores in membrane

Ex: amphotericin & nystatin

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4
Q

Azoles MAO & ex

A

Inhibit 14-alpha-lanosterol demethylase (less ergosterol)

Ex: -azole

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5
Q

Allylamines MAO & ex

A

Inhibit squalene 2,3 epoxidase (less ergosterol)

Ex: Terbinafine

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6
Q

Echinocandins MAO & ex

A

Inhibit 1,3 glucan synthase (less cell wall synthesis)

Ex: -fungin

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