Drugs

Question 1

What are the main classifications of antiseizure medications?

Answer 1

Antiseizure medications are primarily classified into traditional (older) and newer (modern) agents.

Question 2

Which class of antiseizure medications includes Phenytoin and Carbamazepine?

Answer 2

Traditional antiseizure medications.

Question 3

What is the mechanism of action of benzodiazepines in seizure control?

Answer 3

Benzodiazepines enhance the effect of the neurotransmitter GABA at the GABA-A receptor.

Question 4

True or False: Antiseizure medications are always effective in controlling seizures.

Answer 4

False.

Question 5

Fill in the blank: __________ is the first-line treatment for generalized tonic-clonic seizures.

Answer 5

Valproate.

Question 6

What is a common side effect of Lamotrigine?

Answer 6

Skin rash, which can lead to Stevens-Johnson syndrome.

Question 7

Which antiseizure medication is often used in pediatric patients for absence seizures?

Answer 7

Ethosuximide.

Question 8

What is the primary mechanism of action of sodium channel blockers?

Answer 8

They inhibit the influx of sodium ions during action potentials, stabilizing neuronal membranes.

Question 9

Name one antiseizure medication that is contraindicated in pregnancy.

Answer 9

Valproate.

Question 10

True or False: All antiseizure medications have the same side effect profile.

Answer 10

False.

Question 11

What is the importance of therapeutic drug monitoring in antiseizure medications?

Answer 11

To ensure effective drug levels and minimize toxicity.

Question 12

Which newer antiseizure medication is known for its minimal drug interactions?

Answer 12

Levetiracetam.

Question 13

Fill in the blank: __________ is a common side effect of topiramate.

Answer 13

Cognitive impairment.

Question 14

What type of seizures is Gabapentin primarily used for?

Answer 14

Partial seizures and neuropathic pain.

Question 15

What is a unique consideration when prescribing antiseizure medications to children?

Answer 15

Dosing often needs to be adjusted based on weight and growth.

Question 16

Which antiseizure medication is associated with hyperammonemia in children?

Answer 16

Valproate.

Question 17

Name one side effect that can occur with the use of Carbamazepine.

Answer 17

Aplastic anemia.

Question 18

True or False: Antiseizure medications can be abruptly discontinued without risk.

Answer 18

False.

Question 19

Which antiseizure medication is often used as a second-line treatment for status epilepticus?

Answer 19

Phenytoin.

Question 20

What is the role of GABA in the mechanism of action of many antiseizure medications?

Answer 20

GABA is an inhibitory neurotransmitter that helps to reduce neuronal excitability.

Question 21

Fill in the blank: __________ is the most common type of seizure in children.

Answer 21

Febrile seizure.

Question 22

What is the primary goal of antiseizure medication therapy?

Answer 22

To achieve seizure control with minimal side effects.

Question 23

Which antiseizure medication is used to treat Lennox-Gastaut syndrome?

Answer 23

Clobazam.

Question 24

What is a key concern when prescribing antiseizure medications to adolescents?

Answer 24

Potential impact on cognitive development and academic performance.

Question 25

True or False: All antiseizure medications are safe for long-term use in children.

Answer 25

False.