Drugs Flashcards
What are the main classifications of antiseizure medications?
Antiseizure medications are primarily classified into traditional (older) and newer (modern) agents.
Which class of antiseizure medications includes Phenytoin and Carbamazepine?
Traditional antiseizure medications.
What is the mechanism of action of benzodiazepines in seizure control?
Benzodiazepines enhance the effect of the neurotransmitter GABA at the GABA-A receptor.
True or False: Antiseizure medications are always effective in controlling seizures.
False.
Fill in the blank: __________ is the first-line treatment for generalized tonic-clonic seizures.
Valproate.
What is a common side effect of Lamotrigine?
Skin rash, which can lead to Stevens-Johnson syndrome.
Which antiseizure medication is often used in pediatric patients for absence seizures?
Ethosuximide.
What is the primary mechanism of action of sodium channel blockers?
They inhibit the influx of sodium ions during action potentials, stabilizing neuronal membranes.
Name one antiseizure medication that is contraindicated in pregnancy.
Valproate.
True or False: All antiseizure medications have the same side effect profile.
False.
What is the importance of therapeutic drug monitoring in antiseizure medications?
To ensure effective drug levels and minimize toxicity.
Which newer antiseizure medication is known for its minimal drug interactions?
Levetiracetam.
Fill in the blank: __________ is a common side effect of topiramate.
Cognitive impairment.
What type of seizures is Gabapentin primarily used for?
Partial seizures and neuropathic pain.
What is a unique consideration when prescribing antiseizure medications to children?
Dosing often needs to be adjusted based on weight and growth.
Which antiseizure medication is associated with hyperammonemia in children?
Valproate.
Name one side effect that can occur with the use of Carbamazepine.
Aplastic anemia.
True or False: Antiseizure medications can be abruptly discontinued without risk.
False.
Which antiseizure medication is often used as a second-line treatment for status epilepticus?
Phenytoin.
What is the role of GABA in the mechanism of action of many antiseizure medications?
GABA is an inhibitory neurotransmitter that helps to reduce neuronal excitability.
Fill in the blank: __________ is the most common type of seizure in children.
Febrile seizure.
What is the primary goal of antiseizure medication therapy?
To achieve seizure control with minimal side effects.
Which antiseizure medication is used to treat Lennox-Gastaut syndrome?
Clobazam.
What is a key concern when prescribing antiseizure medications to adolescents?
Potential impact on cognitive development and academic performance.
True or False: All antiseizure medications are safe for long-term use in children.
False.
