DRUGS Flashcards
what drugs can cause delirium?
anti-cholinergics
-benzodiazepines
-opiates
-steroids
(antihistamines, mm relaxants, antibiotics can too)
cholinergic inhibitors for Alzheimers
Cholinesterase inhibitors
1. Donepezil (Aricept)
2. Galantamine (Razadyne)
3. Rivastigmine (Exelon)
what med costs 26,500$ per year, approved in 2023, slows decline by 27% over 18 months for early stage alzheimers?
*EARLY STAGE
Lecanemab: IV medication every 2 weeks
side effects: ARIA, infusion related reaction, HEADACHE
what is aducanumab-avwa/aduhelm for?
IV infusion for alzheimers
(shows amyloid related edema in MRI: ARIA-E)
NMDA partial antagonist for alzheimer
namenda/memantine
LEWY BODY DEMENTIA MEDS
ACH inhibitor: rivastigmine
parkinsons sympt: levodopa-carbidopa
treatments for essential tremor
antiepileptics:
1. primidone
2. topirimate
beta-blockers:
-propranolol
or wrist weights
what meds help with CP spasticity?
diazepma
tizanidne
baclofen
injection: botox (botulism A)
what drugs are given to Muscular dystrophy
Gene therapy: elevidys
ASOs
Corticosteroids: prednisone, deflazacort, DEXA
drugs for essential tremors
primidone (antiepileptic)
– propranolol (Beta-blocker) – topirimate- an antiepileptic
parkinson’s meds in progression
- levodopa (sinemet)
- dopamine agonists: requip, mirapex, apokyn, neupro
- COMT-inhibitor: comtan to prevent levodopa breakdown
MAO inhibitor: prevent levodopa breakdown
deep brain stimulation: advanced PD
camped decormia and inverted foot are symptoms of
parkinsons
foot invert: dystonia
camped decormia: leaning tower of pisa syndrome
what is vascular parkinsonism
lower body parkinsonism
(freezing, gait, postural instability)
*extensive subcortical white matter ischemic disease
*step wise deterioration
*half have weakness
what is progressive supranuclear palsy
can’t look up or down
axial rigidity
early falls
*atypical parkinsonism
corticobasal degeneration is what
asymmetric limb dysfunction, alien limb/apraxia
*atypical parkinsonism
