Drugs Flashcards
Omprazole is a
proton pump inhibitor
Contra Indications of Omprazole
Hypersenitivity, Liver Dysfunction, concurrent medications, pregnancy, Abmornal Gastic Acid
Bute is a
NSAID
Example of a Cox 1 inhibitor
Bute, Flunixin
What does NOPS stand for ?
Natually Occuring Prohibited Substnaces
Examples of NOPS substances?
Morphine, Atrophine
How many FEI approved Labs are their?
Five
Regardless of who accompanies the horses the athlete remains the
Person Responsible
Athletes are encouraged to be present themselves
because only the person who witnesses the testing
can
give evidence about procedures and whether they
were conducted according to the rules
Which order are Drug Samples collected in ?
Urine then Blood but if no Urine in 60 minutes then Blood only. Samples are split into A and B Samples
The FEI sampling form is called the
EADCMP
Examples of Anabolic-Androgenic Steriods
Stanozolol , Nandrolone
The presence of a Banned Substance in the Horse’s sample, the use, the administration, the trafficking as well as the mere possession of a Banned Substance are
Anti-Doping Rule Violations
What is WADA
World Anti-Doping Agency
Horses cannot be treated in
their own stables are shows.
The withdrawal time for a drug must be decided
upon by the treating veterinarian and is likely to be based on the detection time and an added safety
margin.
Well-established fact that there may be a difference in detection time for a substance
depending on the route of administration i.e.
intra-articular(i.a.), intravenous(i.v), intramuscular(i.m) and subcutaneous(s/c).
Clenbuterol Detection Time
7 Days
DEMBREXINE Detection Time
5 days
Flunixin Detection Time
6 Days
Bute Detection Time
7 Days (Both Oral and IV)
Ketoprofen detection times
Topical treatment has resulted in prolonged detection times.
Tildren detection Time
28 days
Suxibuzone
Granules converted to phenylbutazone by liver has palatable sugar coating
Flunixin
Injection /Paste/granules -treatment of toxaemia
Carprofen
Donkeys as not broken down as rapidly as other NSAIDs
Pencillins
Broad Spectrum
Tetracyclines
Bacterostatic. Broad Spectrum . IV or by mouth.
Antiseptics
Applied to living tissue to reduce possibility of infection
Most antiseptics exert their effect by
-Inhibiting enzymes in the cell.
-Altering proteins found inside the cell of the bacterium.
-Damaging the cell membrane
Bacteriostatic
Inhibit bacteria growing or replicate so allow own immune system to destroy them
Bacteriocidal
Kill the bacteria
Domosedan detection time
2 days
FEI has two lists of drugs
Banned and Controlled
Minising risks of contamination to Hay/Feed/Bedding
Reputable Supplier
NOPS Testing
Sample/Batch Numbers
Store carefully
Clean
Record Suppliments
Paracetanol is
office license in horses but used in lami
When would you Xray for Lami
2 weeks
Diagnosising PPID
excessive pituitary response to the administration of Thyrotropin-releasing hormone (TRH) in horses with PPID when compared to normal horses.
Equine Metabolic Syndrome diagnosised by
Resting Insulin Concentration
Significant lami can increase risk of
abccesses
When would you test insulin in lami
after 2 weeks then every 4 weeks until under control
How is Arthamid delievered
IA.
Conditions that respond to treatment with Arthramid® Vet include
acute and chronic synovitis, osteoarthritis and degenerative joint disease
Arthamid is
polyacrylamide hydrogel. Integrates into the joint tissue providing shock absorption to the joint
Metcam is an NSAID which can be administers via
IV
Sedative is a drug
that produces mental calmness through sleepiness
Tranquilliser achieves
mental calming through reduced anxiety
ACP Acepromazine is a
tranquilliser
More ACP
does not result in a deeper effect
ACP can take
40-60 minutes but IV is quicker (as is IM)
Detomidine, Romifidine, Xylazine
are Alpha 2 adrenocepter agonists
Alpha 2 drugs are
highly toxic
Detomidine, Romifidine, Xylazine work via
resulting through inbition of norepinephrine release from noradrenergic recepters in a section of the brainsteam
Detomidine and Romifidine
40 - 60 minutes
Omeprazole is banned under BHA rules and has a detection time
48 hours
Concurrent use of NSAIDs with TILDREN may increase the risk of
renal issues
During the 2019 UK Equine Influenza, 228 outbreaks were recorded.
more than any other country
CANTER
Controlling ANTiparasitic Resistance in Equines Responsibly.
Tildren is given
in a dilute form by intravenous infusion over one hour.