Drug Toxicities, Dumping Syndrome vs. Hiatal Hernia Flashcards
What is the therapeutic range for Lithium?
0.4-1.4
What is the toxic level of Lithium?
2.0+
What is the therapeutic range for Digoxin?
0.8-2.0
What is the toxic level of Digoxin?
2+
What is the therapeutic range of Aminophylline?
10-20
What is aminophylline used for?
Tx. relaxed muscles spasms in bronchospasms (for airway)
What is the toxicity level of Aminophylline?
20+
What is the therapeutic range of Bilirubin?
10-20
-Have parents bring baby to hospital if bilirubin around 14-15
What is the toxicity level of Bilirubin in the body?
20+
-Kernicterus is bili in the brain nd CSF baby could die (aseptic sterile meningitis)
–> Place baby in OPISTHODOMS position (ON THEIR SIDE) because baby hyperextends w/ stiff back
—DO NOT PLACE SUPINE OR PRONE, Place baby on their SIDE
What is lithium used for?
Bipolar and manic episodes (not depression)
What is Digoxin used for?
Tx. Afib and CHF
What is Phenytoin used for?
Tx. seizure med
What is Dumping Syndrome?
GI contents dump to quickly into the duodenum
Speed Issue
Food moves in the RIGHT DIRECTION but the WRONG RATE
What is the threptic level for Phenytoin
10-20
Toxicity= 30+
S/S of Dumping Syndrome
Drunk + Shock+ Acute abd distress
-Drunk: staggered gate, delayed reaction. labile emotion, poor coordination
-Shock: HToN, Tachy, cool, clammy
-Abd distress: Borborygmi, doubling over, cramping distention, diarrhea
What is the goal for Dumping Syndrome?
Get stomach to empty SLOWER
TX Dumping Syndrome
HOB: Low HOB position eat lying down on side
H2O: Decrease H2O @meal drink 1hr before/after meals
CHO: Low CHO diet Decrease CHO, CHO digest fast
If you want stomach to be sLOW you want everything to be LOW
What is Hiatal Hernia
Regurgitation of acid into esophagus because upper part of stomach herniates into the base of the esophagus (basically 2 stomachs)
**Direction Issue*
Food moves in the WRONG DIRECTION but at the Right Rate
S/S of Hiatal Hernia
GERD: heart burn & indigestion that occurs when you Lie down, after you eat
-Depends on position & mealtime
What is the goal for Hiatal Hernia
Get stomach to empty faster (nothing in the stomach means no reflux)
Tx Hiatal Hernia
HOB: HIGH HOB position 1 hr post meal
H2O: High fluid intake @meals
CHO: High CHO diet (high CHO & low Protein)
In hiatial Hernia, you want everything to be High
