Drug Sources & Classifications Flashcards

1
Q

Define drugs

A

A chemical substance of known structure, other than a nutrient or essential dietary ingredient, which, when administered to a living organism, produces a biological effect

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2
Q

Most prescribed drugs in Ireland

A

Cardiovascular

CNS

Pain

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3
Q

3 types of names a drug may have

A
  1. Exact or abbreviated chemical name
  2. Official generic name
  3. Brand or commercial name
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4
Q

What is the MOA of fluoxetine (hydrochloride)

Hence what is it used for

A

Highly specific serotonin uptake inhibitor, used as an antidepressant

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5
Q

what is common ending of cholesterol lowering drugs

A

Statins

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6
Q

What is the common ending of anti-ulcer drugs

A

Prazole (proton pump inhibitors)

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7
Q

What is the classification of drugs based on

A
  1. Chemical structure
  2. Mechanism of action
  3. Response produced
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8
Q

Give an example of beta lactam antibiotics

A

Penicillin

(all share beta lactam ring)

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9
Q

Give an example of drugs classed according to their mechanism of action

What is their function

A

Beta blocker (propranolol)

  • Drugs for lowering BP
  • Block beta adrenoceptors
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10
Q

Give an example of drugs classed according to the response produced

A

Antihypertensive agents - physiological response is to lower BP

e.g.

  • beta blockers
  • ACE inhibitors
  • Diuretics

All reduce BP differently

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11
Q

Name the 5 sources of drugs

A
  1. Plants
  2. Micro-organisms
  3. Animals
  4. Synthetic
  5. Products of genetic engineering
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12
Q

What plant source is used to treat congestive heart failure

A

Digitalis from foxglove

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13
Q

What plant does morphine come from

A

Opium poppy

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14
Q

Give an example of a drug derived from microorganisms

A

Benzyl penicillin from penicillum mould

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15
Q

Where does insulin come from

A

Pancreatic extracts

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16
Q

What synthetic drugs have an antibacterial effect

What molecule is responsible for this effect

A

Prontosil

Sulphanilamide and sulphonamides - the sulphanilamide portion of the prontosil molecule is responsible for its antibacterial effect

17
Q

What is recombinant insulin produced from

A

From the insertion of the human insulin gene into E coli, which then produces insulin in culture

18
Q

What is the MW of most drugs

A

100-1000