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Step 1 Pharm > Drug Reactions > Flashcards

Drug Reactions Flashcards

1
Q

cocaine, sumatriptan, ergot alkaloids

A

coronary vasospasm

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2
Q

VANComycin Adenosine, Niacin, Ca++ channel blockers

“VANC”

A

cutaneous flushing

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3
Q

doxorubicin (adriamycin), daunorubicin

A

dilated cardiomyopathy

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4
Q

class III (sotalol) & class IA (quinidine) antiarrhythmics

A

torsades de pointes

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5
Q

Clozapine, Carbamazepine, Colchicine, Propylthiouracil, Methimazole, Dapsone

A

agranulocytosis

“Agranulocytosis Could Certainly Cause Pretty Major Damage”

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6
Q

chloramphenicol, benzene, NSAIDs, propylthiouracil, methimazole

A

aplastic anemia

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7
Q

methyldopa, penicillin

A

direct coomb’s - positive hemolytic anemia

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8
Q

chloramphenicol

A

gray baby syndrome

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9
Q

Isoniazid (INH), Sulfonamides, Primaquine, Aspirin, Ibuprofen, Nitrofurantoin

A

hemolysis in G6PD deficient patients

“hemolysis IS PAIN”

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10
Q

Phenytoin, Methotrexate, Sulfa drugs

A

megaloBLASTic anemia

“having a BLAST with PMS”

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11
Q

OCPs (estrogens)

A

thrombotic complications

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12
Q

ACE inhibitors

A

cough

remember – ARBs (losartan) = no cough

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13
Q

BLeomycin, Amiodarone, Busulfan

A

pulmonary fibrosis

“its hard to BLAB when you have pulmonary fibrosis”

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14
Q

erythromycin

A

acute cholestatic hepatitis, jaundice

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15
Q

Halothane, Amanita phalloides, Valproic acid, Acetaminophen

“liver HAVAc”

A

focal to massive hepatic necrosis

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16
Q

INH (Isonizaid)

A

hepatitis

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17
Q

clindamycin, ampicillin

A

pseudomembranous colitis

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18
Q

glucocorticoid withdrawal (HPA suppression)

A

adrenocortical insufficiency

19
Q

Spironolactone, Digitalis, Cimetidine, chronic Alcohol use, estrogens, Ketoconazole

A

gynecomastia

“Some Drugs Create Awkward Knockers”

20
Q

tamoxifen, clomiphene

A

hot flashes

21
Q

niacin, tacrolimus, protease inhibitors, HCTZ, corticosteroids

A

hyperglycemia

22
Q

lithium, amiodarone, sulfonamides

A

hypothyroidism

23
Q

glucocorticoids, protease inhibitors

A

fat redistribution

24
Q

phenytoin, verapamil

A

gingival hyperplasia

25
Q

furosemide, thiazides, niacin, cyclosporine

26
Q

Fibrates, Niacin, Colchicine, Hydroxychloroquine, Ingerferon-alpha, Penicillamine, Statins, Glucocorticoids

A

myopathies

“Fish N CHIPS Give you myopathies”

27
Q

corticosteroids, heparin

A

osteoporosis

28
Q

Sulfonamides, Amiodarone, Tetracycline

A

photosensitivity

“SAT for a photo”

29
Q

Penicillin, Ethosuximide, Carbamazepine, Sulfa drugs, Lamotrigine, Allopurinol, Phenytoin, Phenobarbital

A

rash (stevens-johnson sundrome)

“bad rash after a PEC SLAPP”

30
Q

Hydralazine, INH, Procainamide, Phenytoin

A

SLE

“its not HIPP to have lupus”

31
Q

tetracyclines

A

teeth (kids)

32
Q

fluoroquinolones

A

tendonitis, tendon rupture, cartilage damage

33
Q

lithium, demeclocycline

A

diabetes insipidus

34
Q

expired tetracycline

A

Fanconi’s syndrome (remember ass. w/ amino acid Cysteine)

35
Q

cyclophosphamide, ifosfamide

prevent by?

A

hemorrhagic cystitis

prevent by coadministering w/ mesna

36
Q

methicillin, NSAIDs, furosemide

A

interstitial nephritis

37
Q

carbamazepine, cyclophosphamide

38
Q

quinidine, quinine

A

cinchonism

39
Q

antipsychotics, reserpine, methoclopramide

A

parkinson-like syndrome

40
Q

Isoniazid, Buproprion, Imipenem/cilastatin, Tramadol, Enflurane, Methoclopramide

A

seizures

“with seizures, I BITE My tongue”

41
Q

antipsychotics

A

tardive dyskinesia

42
Q

atropine, TCAs, H1-blockers, neuroleptics

A

antimuscarinic

43
Q

metronidazole, certain cephalosprins, procarbazine, 1st gen sulfonylureas

A

disulfiram-like reaction

44
Q

aminoglycosides, vancomycin, loop diuretics, cisplatin

A

nephrotoxicity/ototoxicity

Step 1 Pharm (19 decks)

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