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Step 1 Pharm > Antidotes > Flashcards

Antidotes Flashcards

1
Q

Acetaminophen OD

A

N-acetylcysteine

(replenishes glutathione)

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2
Q

Salicylates

A

Dialysis

NaHCO3

(alkalinize urine)

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3
Q

Amphetamine OD

A

NH4Cl

(acidify urine)

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4
Q

Acetylcholinesterase inhibitors,

organophosphates

A

Atropine, pralidoxime

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5
Q

Antimuscarinics, anticholinergics

A

Physostigmine salicylate

Control hyperthermia

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6
Q

Beta-blocker OD

A

Glucagon

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7
Q

Digitalis OD

(4)

A

Normalize K+

Anti-dig Fab

Lidocaine

Mg2+

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8
Q

Iron

A

Deferoxamine, deferasirox

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9
Q

Lead

A

CaEDTA, dimercaprol, succimer, penicillamine

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10
Q

Mercury, arsenic, gold

A

Dimercaprol (BAL), succimer

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11
Q

Copper, arsenic, gold

A

Penicillamine

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12
Q

Cyanide

A

Nitrite + thiosulfate

hydroxocobalamin

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13
Q

Methemoglobin

A

Methylene blue

Vitamin C

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14
Q

Carbon monoxide

A

100% O2

Hyperbaric O2

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15
Q

Methanol, ethylene glycol

A

Fomepizole > ethanol

dialysis

Fomepizole blocks Alcohol Dehydrogenase (in Cytosol)

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16
Q

Opiod OD

A

Naloxone/naltrexone

17
Q

Benzodiazepine OD

Note: Increase FREQUENCY of Cl- channel opening of GABAa

A

Flumazenil

18
Q

Tricyclic antidepressant OD

A

NaHCO3

(plasma alkalinization)

19
Q

Heparin

A

Protamine

20
Q

Warfarin

A

Vit K (long term reversal), fresh frozen plasma (immediate reversal)

21
Q

tPA, streptokinase, urokinase

A

Aminocaproic acid

22
Q

Theophylline

A

Beta-blocker

Step 1 Pharm (19 decks)

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