Drug reactions Flashcards

1
Q

Which drugs can cause coronary vasospasm?

A
  • Amphetamines
  • Cocaine
  • Ergot alkaloids
  • Sumatriptan
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2
Q

Which drugs can cause cutaneous flushing as an adverse effect?

A
  • Vancomycin
  • Adenosine
  • Niacin
  • Nitrates
  • Calcium channel blockers
  • Echinocandins

Remember: VANCCE

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3
Q

Which drugs cause dilated cardiomyopathy?

A
  • Anthracyclines
    • Doxorubicin (Adriamycin)
    • Daunorubicin
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4
Q

Used to prevent or decrease heart damage caused by doxorubicin

A

Dexrazoxane

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5
Q

Which drugs can cause torsades de pointes?

A
  • Anti-Arrhythmics (class IA, III)
  • anti-Biotics (eg, macrolides)
  • anti“C”ychotics (eg, haloperidol)
  • antiDepressants (eg, TCAs)
  • antiEmetics (eg, ondansetron, cisapride)
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6
Q

What cardiac adverse effect can result from either cocaine or sumatriptan use?

A

Coronary vasospasm

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7
Q

What is the major adverse effect of niacin use?

A

Flushing

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