Anti-hypertensive drugs - Nitrates Flashcards
1
Q
Are nitrates more effective as preload or afterload reducers?
A
Preload reducers
2
Q
Does isosorbide dinitrate dilate veins or arteries more?
A
Veins
3
Q
How does nitric oxide cause smooth muscle relaxation?
A
By increasing cGMP concentration
4
Q
Vasodilation using nitroglycerin is caused by the release of what chemical in smooth muscle?
A
Nitric oxide
5
Q
What are two indications for the use of nitroglycerin?
A
Angina and pulmonary edema
6
Q
Name four adverse effects of nitroglycerin
A
- Reflex tachycardia
- Hypotension
- Flushing
- Headache
