Anti-hypertensive drugs - Hydralazine Flashcards
1
Q
Which does hydralazine reduce: afterload or preload?
A
Afterload
2
Q
When hydralazine is administered, which vessels dilate more: veins or arterioles?
A
Arterioles
3
Q
Hydralazine causes smooth muscle relaxation by ____
A
Increasing concentrations cGMP
4
Q
Which cardiac adverse effect results from the drop in blood pressure induced by hydralazine?
A
Tachycardia
5
Q
Does hydralazine cause fluid excretion or retention?
A
Retention
6
Q
Hydralazine can induce which autoimmune complication in patients?
A
Systemic lupus erythematosus
7
Q
Why is hydralazine contraindicated in patients with angina or coronary artery disease?
A
Because it can cause compensatory tachycardia
8
Q
Hydralazine is frequently coadministered with a ____ to ____
A
- β-blocker
- Prevent reflex tachycardia
