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Pharm > drug reactions > Flashcards

drug reactions Flashcards

1
Q

coronary vasospasm

A

cocaine
sumatriptan
ergot alkaloids

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2
Q

cutaneous flushing

A

vancomycin
adenosine
niacin
Ca channel blockers

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3
Q

dilated cardiomyopathy

A

anthracyclines - doxorubicin, daunorubicin

dexrazoxane

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4
Q

torsades de pointes

A 
class III antiarrhythmics - sotalol 
class IA antiarrhythmics - quinidine 
macrolides
antipsychotics
TCAs
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5
Q

adrenalcortical insufficiency

A

HPA suppression secondary to glucocorticoid withdrawl

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6
Q

hot flashes

A

tamoxifen

clomiphene

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7
Q

hyperglycemia

A 
tacrolimus 
protease inhibitors 
niacin 
HCTZ
corticosteroids
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8
Q

hypothyroidism

A

lithium
amiodarone
sulfonamides

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9
Q

acute cholestatic hepatitis, jaundice

A

erythromycin

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10
Q

diarrhea

A 
metformin 
erythromycin 
colchicine 
orlistat
acarbose
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11
Q

hepatic necrosis

A

halothane
amanita phalloides
valproic acid
acetaminophen

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12
Q

hepatitis

A 
rifampin 
isoniazid 
pyrazinamide
statins 
fibrates
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13
Q

pancreatitis

A 
didanosine
corticosteroids 
alcohol
valproic acid 
azathioprine
diuretics (furosemide, HCTZ)
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14
Q

pseudomembranous colitis

A

clindamycin
ampicillin
cephalosporins

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15
Q

agranulocytosis

A 
ganciclovir 
clozapine 
carbamazapine 
colchicine 
methimazole 
propylthiouracil
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16
Q

aplastic anemia

A 
carbamazepine 
methimazole 
NSAIDs 
benzene 
chloramphenicol
propylthiouracil
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17
Q

direct coombs positive hemolytic anemia

A

methyldopa

penicillin

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18
Q

gray baby syndrome

A

chloramphenicol

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19
Q

hemolysis in G6PD deficiency

A 
isoniazid 
sulfonamides 
dapsone 
primaquine 
aspirin
ibuprofen 
nitrofurantoin
20
Q

megaloblastic anemia

A

phenytoin
methotrexate
sulfa drugs

21
Q

thrombocytopenia

22
Q

thrombotic complications

23
Q

fat redistribution

A

protease inhibitors

glucocorticoids

24
Q

gingival hyperplasia

A

phenytoin
Ca channel blockers
cyclosporine

25
Q

hyperuricemia

A 
pyrazinamide 
thiazides 
furosemide 
niacin 
cyclosporine
26
Q

myopathy

A 
fibrates 
niacin 
colchicine 
hydroxychloroquine 
IFNa
penicillamine 
statins 
glucocorticoids
27
Q

osteoporosis

A

corticosteroids

heparin

28
Q

SLE-like syndrome

A 
sulfa drugs 
hydralazine 
isoniazid 
procainamide 
phenytoin 
etanercept
29
Q

teeth discoloration

A

tetracycline

30
Q

photosensitivity

A

sulfonamides
amiodarone
tetracyclines

31
Q

tendonitis, tendon rupture, cartilage damage

A

fluoroquinolones

32
Q

cinchonism

A

quinidine

quinine

33
Q

parkinson-like syndrome

A

antipsychotics
reserpine
metoclopramide

34
Q

seizures

A

isoniazid
bupropion
imipenem / cislastatin
enflurane

35
Q

tardive dyskinesia

A

antipsychotics

metoclopramide

36
Q

diabetes insipidus

A

lithium

demeclocycline

37
Q

fanconi syndrome

A

expired tetracyclines

38
Q

hemorrhagic cystitis

A

cyclophosphamide

ifosfamide

39
Q

interstitial nephritis

A

methicilin
NSAIDs
furosemide

40
Q

SIADH

A

carbamezepine
cyclophosphamide
SSRIs

41
Q

dry cough

42
Q

pulmonary fibrosis

A

bleomycin
amiodarone
busulfan
methotrexate

43
Q

antimuscarinic

A

atropine
TCAs
H1 blockers
antipsychotics

44
Q

disulfiram-like rxn

A 
metronidazole 
certain cephalosporins
griseofulvin 
procarbazine 
1st generation sulfonylureas
45
Q

nephrotoxicity, ototoxicity

A

aminoglycosides
vancomycin
loop diuretics
cisplatin

46
Q

CYP inducers

A 
chronic alcohol 
st johns wort 
phenytoin 
phenobarbital 
nevirapine 
rifampin 
griseofulvin 
carbamazepine
47
Q

CYP inhibitors

A 
acute alcohol
ritonavir 
amiodarone 
cimetidine 
ketoconazole 
sulfonamides 
isoniazid 
grapefruit juice 
quinidine 
macrolides

Pharm (8 decks)

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