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STEP 1 Pharm > Drug reactions > Flashcards

Drug reactions Flashcards

1
Q

Coronary vasospasm

A

Triptans, ergots, cocaine

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2
Q

Cutaneous flushing

A

Vancomycin, adenosine, niacin, CCBs

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3
Q

Dilated cardiomyopathy

A

Alcohol, doxo/daunorubin,

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4
Q

Torsades de points

A

Type III antiarrhythmics, class 1a antiarrhythmics, macrolides, tricyclics, antipsychotics.

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5
Q

Adrenocortical insufficiency

A

glucocorticoid withdrawal

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6
Q

Hot flashes

A

Tamoxifen, clomiphene

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7
Q

Hyperglycemia

A

Tacrolimus, protease inhibitors, niacin, HCTZ, beta blockers, corticosteroids

Taking pills necessitates having blood checked

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8
Q

Hypothyroidism

A

Lithium, amiodarone, sulfonamides

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9
Q

Acute cholestatic hepatitis

A

Erythromycin, also causes jaundice

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10
Q

Diarrhea

A

Metformin, erythromycin, colchicine, orlistat, acarbose

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11
Q

Hepatic necrosis

A

Halothana, amantin, valproate, acetaminophen

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12
Q

Hepatitis

A

Isoniazid

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13
Q

Pancreatitis

A

didanosine, coricosteroids, alcohol, valproate, azathioprine, diuretics

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14
Q

Pseudomembranous colitis

A

Clindamycin, ampicillin, cephalosporins

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15
Q

Agranulocytosis

A

Dapsone, clozapine, carbamazepine, colchicine, methimazole, propylthiouricil

“Drugs CCCrush Myeloblasts and Promyelocytes”

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16
Q

Aplastic anemia

A

Carbamazepine, methimazole, nsaids, benzene, chloramphenicol, propylthiouracil

17
Q

Coombs positive hemolytic anemia

A

methyldopa, penicillin

18
Q

Gray baby syndrome

A

Chloramphenicol

19
Q

Hemolysis in g6pd

A

Sulfa drugs, fava beans, isoniazid, primaquin

20
Q

Megaloblastic anemia

A

phenytoin, methotrexate, sulfa drugs

21
Q

Fat redistributioin

A

protease inhibitors and glucocorticoids

22
Q

gingival hyperplasia

A

Phenytoin, verapamil, cyclosporine, nifedipine

23
Q

Hyperuricemia

A

Pyrazinamide, thiazides, furosemide, niacin

24
Q

Steven’s Johnson syndrome

A

Antiepileptics, allopurinol, sulfas, penicillin

25
Q

Sle like syndrome

A

Sulfa drugs, hydralazine, INH, phenytoin, etanercept

26
Q

CYP inducers

A

Modafinil

C - carbamazepine
Rifampin
A
Phenobarbital

Griseofulvin
Phenytoin
St john’s wort

Nevirapine

27
Q

CYP substrates

A 
Antidepressants
antipsychotics
antiepileptics
Anesthetics
Theophylline
Warfarin
Statin
OCP
28
Q

CYP inhibitors

A 
Acute
Gemfibrozil
Ciprofloxacin
Isoniazid
Grapefruit juice
quinidine
amiodarone 
ketoconazole
Macrolides
Sulfonamides
Cimetidine
Ritonavir
29
Q

Sulfa drugs

A

Probenecid, furosemide, acetazolamide, celecoxib, thiazides, sulfonamides, sulfonylureas, sulfazalazine

30
Q

Sulfa drug allergy

A

Can cause SJS, fever, hemolytic anemia, thrombocytopenia, agranulocytosis, and hives.

STEP 1 Pharm (17 decks)

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